ntshav txhaws cov proteins tsim thrombin, ib qho enzyme uas hloov fibrinogen rau fibrin, thiab cov tshuaj tiv thaiv uas ua rau tsim cov fibrin clot.
Dab tsi enzyme hloov fibrinogen rau fibrin?
Nyob ntawm cov kauj ruam enzymatic, muaj thrombin- catalyzed cleavage ntawm fibrinopeptides ntawm fibrinogen los tsim cov fibrin monomer. Thrombin yog ib qho tshwj xeeb serine protease thaum ua kom nws cov zymogen, prothrombin, ib txwm muaj nyob rau hauv cov ntshav.
Qhov twg fibrinogen hloov mus rau fibrin?
fibrin tsim
chains; Nws yog tsim los ntawm fibrinogen, ib qho protein uas muaj kuab heev uas yog tsim los ntawm lub siab thiab pom hauv cov ntshav plasma. Thaum cov ntaub so ntswg puas ua rau los ntshav, fibrinogen hloov dua siab tshiab ntawm lub qhov txhab rau hauv fibrin los ntawm kev ua ntawm thrombin, ib qho enzyme.
Leej twg secretes fibrinogen?
Fibrinogen yog tsim thiab tso rau hauv cov ntshav feem ntau los ntawm daim siab hepatocyte cells.
Qhov twg ua rau hloov pauv ntawm fibrinogen rau fibrin?
Fibrinogen (Factor I) yog 340-kDa glycoprotein uas yog tsim los ntawm daim siab (41). Nws yog qhib rau fibrin los ntawm thrombin, nthuav tawm ntau qhov chaw polymerization uas tau hla mus rau qhov tsis txaus ntseeg fibrin clot nyob rau hauv kev koom tes ntawm activated factor XIII (41, 42).
