ntshav txhaws cov proteins tsim thrombin, ib qho enzyme uas hloov fibrinogen rau fibrin, thiab cov tshuaj tiv thaiv uas ua rau tsim cov fibrin clot.
Yuav ua li cas fibrinogen hloov mus rau fibrin?
Fibrinogen yog ib qho macromolecule soluble, tab sis tsim cov hlab ntsha tsis sib haum lossis gel ntawm kev hloov mus rau fibrin los ntawm kev ua ntawm serine protease thrombin, uas yog qhib los ntawm cascade ntawm cov tshuaj tiv thaiv enzymatic. tshwm sim los ntawm kev raug mob ntawm phab ntsa ntawm cov hlab ntsha, cov qe ntshav liab, lossis lwm qhov chaw (Fig. 13.1).
Hom cell twg hloov fibrinogen rau fibrin?
Cov no platelets muaj thrombin receptors ntawm lawv qhov chaw uas khi cov ntshav thrombin molecules, uas tig mus hloov cov kua dej fibrinogen hauv cov ntshav mus rau hauv fibrin ntawm qhov txhab. Fibrin tsim cov kab ntev ntev ntawm cov protein uas tsis sib haum xeeb uas khi rau cov platelets.
YPob platelets hloov fibrinogen rau fibrin?
Thaum cov ntaub so ntswg puas ua rau los ntshav, fibrinogen hloov ntawm lub qhov txhab mus rau hauv fibrin los ntawm kev ua ntawm thrombin, ib qho enzyme ua ntshav. Fibrin molecules tom qab ntawd ua ke los ua cov fibers ntev ntev uas cuam tshuam cov platelets, tsim cov pob txha loj uas maj mam tawv thiab sib cog lus los tsim cov ntshav txhaws.
fibrinogen hloov mus ua dab tsi?
Thaum lub sijhawm coagulation, fibrinogen hloov mus ua insoluble fibrin(Daim duab 1). Fibrin tsim muaj thrombin-mediated proteolytic cleavage thiab tshem tawm ntawm N-terminal fibrinopeptides los ntawm Aα thiab Bβ chains.
