Acetyl-CoA yog tsim los ntawm oxidative decarboxylation ntawm pyruvate los ntawm glycolysis, uas tshwm sim hauv mitochondrial matrix, los ntawm oxidation ntawm cov saw ntev fatty acids, los yog los ntawm oxidative degradation ntawm tej yam amino acids. Acetyl-CoA ces nkag mus rau hauv lub voj voog TCA uas nws tau oxidized rau lub zog tsim.
pyruvate rau Acetyl-CoA tshwm sim nyob qhov twg?
Nyob rau hauv prokaryotes, nws tshwm sim hauv cytoplasm. Zuag qhia tag nrho, pyruvate oxidation converts pyruvate-ib peb-carbon molecule-rau hauv acetyl CoAstart ntawv, C, o, A, cov ntawv kawg-ib ob-carbon molecule txuas nrog Coenzyme A-ua cov ntawv NADHstart, N, A, D, H, xaus cov ntawv thiab tso tawm ib qho carbon dioxide molecule hauv cov txheej txheem.
Qhov tseem ceeb ntawm Acetyl-CoA yog dab tsi?
SOURCES OF ACETYL CoA
- YGlycolysis ntawm qabzib.
- Oxidation ntawm fatty acids.
- Amino acid deamination.
Acetyl-CoA tuaj qhov twg los rau kev sib xyaw fatty acid?
Fatty acids yog synthesized hauv cytosol, whereas acetyl CoA yog tsim los ntawm pyruvate hauv mitochondria. Yog li ntawd, acetyl CoA yuav tsum raug xa los ntawm mitochondria mus rau cytosol.
Acetyl-CoA hloov mus rau dab tsi?
Nws tuaj yeem hloov mus rau fatty acids, uas tig mus rau: triglycerides (triacylglycerols) Tshawb. phospholipids.
