Auer rods yog ib qho cim ntawm mob myeloid leukemia tab sis qee zaus pom hauv myelodysplastic syndromes (MDSs) lossis mob myelomonocytic leukemia mob myelomonocytic leukemia Chronic myelomonocytic leukemia (CMML) yog ib qho kev kho mob heterogeneous uas muaj qhov tsis zoo [1]. CMML, ib zaug muab faib ua MDS raws li kev faib tawm Fab Kis-Asmeskas-British, tam sim no tau lees paub los ntawm WHO kev faib tawm raws li kev sib tshooj MDS / myeloproliferative neoplasm (MPN) [1]. https://www.ncbi.nlm.nih.gov › pmc › articles › PMC5973924
Lub xyoo 2016 WHO piv rau 2008 WHO Cov Txheej Txheem rau Kev kuaj mob ntev …
tsis tshua muaj tshwm sim nrog tsawg dua 5% tawg.
AML hom twg muaj Auer rods?
Auer rods (los yog Auer lub cev) yog cov loj, crystalline cytoplasmic suav nrog lub cev qee zaum pom hauv myeloid blast cells thaum mob myeloid leukemia, mob qog nqaij hlav promyelocytic, thiab qib siab myelodysplastic syndromes thiab myeloproliferative disorders.
Tus kab mob leukemia twg muaj Auer rods?
Auer rods yog lub cim ntawm mob myeloid leukemiatab sis qee zaus pom hauv myelodysplastic syndrome (refractory anemia nrog ntau tshaj blasts hom 2) lossis CMML mob, thiab tsis tshua muaj nyob rau hauv cov neeg mob tsawg dua. tshaj 5% blasts [3, 4].
Tus kab mob leukemia twg yog txuam nrog cov hlwb uas muaj ntau yam Auer rods?
mob promyelocytic leukemia yog tus yam ntxwv los ntawm atypical promyelocytes uas tuaj yeem ua tauhypergranular nrog "daim duab yim" nuclei, ntau cytoplasmic granules, thiab pob ntawm Auer rods, los yog hypogranular nrog zoo xws li nuclear zoo tab sis indistinct cytoplasmic granules.
Koj puas pom Auer rods hauv CML?
Ib daim ntawv tshwj xeeb ntawm AML hu ua mob promyelocytic leukemia (APL) paub tias muaj ntau yam promyelocytes nrog ntau Auer rods. Lawv kuj tuaj yeem pom nyob rau hauv kev kub ntxhov nyob rau hauv mob myelogenous leukemia (CML). Auer rods yeej tsis pom hauv lymphoblasts.