Frameshift mutations tshwm sim thaum qhov ib txwm ua ntawm codons cuam tshuam los ntawm kev ntxig lossis tshem tawm ntawm ib lossis ntau dua nucleotides, muab cov nucleotides ntxiv lossis tshem tawm tsis yog ntau yam. ntawm peb.
Vim li cas frameshift mutation tshwm sim?
Feem ntau, kev hloov pauv hloov tshwm sim tshwm sim los ntawm kev hloov pauv yuam kev thaum kho DNA lossis rov ua dua. Lawv kuj tuaj yeem tshwm sim los ntawm kev raug acridine dyes, uas muaj peev xwm ua rau muaj kev hloov pauv hloov pauv.
Yuav ua li cas mutagen ua rau kev hloov pauv hloov pauv?
Proflavin yog acridine dye uas intercalates nws tus kheej ntawm lub hauv paus khub ntawm DNA saw thiaj li ua rau poob los yog nce ntawm ib zaug xwb nucleotide. Cov noob hloov pauv hloov lub hauv paus ua ntu zus ntawm tag nrho cov kab mob caj ces los ntawm qhov kev hloov pauv hu ua frameshift mutation.
Qhov cuam tshuam ntawm kev hloov pauv hloov pauv yog dab tsi?
Ib qho kev hloov pauv yuav nyob rau hauv dav ua rau kev nyeem cov codons tom qab kev hloov pauv mus rau code rau cov amino acids sib txawv. The frameshift mutation will also alter the first stop codon ("UAA", "UGA" or "UAG") encountered in the sequence.
Dab tsi yog frameshift mutation Nws cuam tshuam kev ua haujlwm ntawm cov protein li cas?
Frameshift kev hloov pauv yog qhov tshwm sim ntawm kev ntxig lossis tshem tawm uas hloov pauv qhov kev nyeem ntawv ntawm triplet codons, yog li hloov pauv kev txhais lus thiab hloov cov qauv thiabKev ua haujlwm ntawm cov khoom lag luam protein.
