Nws yog tsim tawm by recombinant DNA thev naus laus zis siv cov kab mob ntawm tes ntawm tes . Cov tshuaj no muaj nyob rau hauv daim ntawv syringe prefilled thiab yooj yim cwj mem rau subcutaneous self-administered koob 1. Ib qho biosimilar tshiab rau adalimumab, lub npe hu ua adalimumab-adaz, tau pom zoo los ntawm FDA thaum Lub Kaum Hli 31, 2018.
adalimumab ua li cas?
HUMIRA yog tsim tawm los ntawm cov thev naus laus zis DNA rov ua dua hauv cov kab mob qog noj ntshav ntawm testhiab tau ua kom huv si los ntawm cov txheej txheem uas suav nrog cov kab mob tshwj xeeb inactivation thiab tshem tawm cov kauj ruam. Nws muaj 1330 amino acids thiab muaj qhov hnyav molecular ntawm kwv yees li 148 kilod altons.
adalimumab tuaj qhov twg?
History. Adalimumab yog thawj tus tib neeg monoclonal antibody pom zoo los ntawm US Food and Drug Administration (FDA). Nws tau muab los ntawm phage zaub.
Cov khoom xyaw hauv adalimumab yog dab tsi?
Txhua 0.8 mL ntawm HUMIRA muaj adalimumab (40 mg), citric acid monohydrate (1.04 mg), dibasic sodium phosphate dihydrate (1.22 mg), mannitol (9.6 mg), monobasic sodium phosphate dihydrate (0.69 mg), polysorbate 80 (0.8 mg), sodium chloride (4.93 mg), sodium citrate (0.24 mg) thiab dej txhaj tshuaj, USP.
Yog HUMIRA tsim los ntawm nas?
Humira yog tib neeg cov tshuaj tiv thaiv tag nrho, lub ntsiab lus nws tsis muaj cov khoom nas, Stoffel tau hais. Remicade, ntawm qhov tod tes, yog ib feem ua los ntawm nasDNA.
