2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Txoj kev hloov pauv yog ib pawg loj ntawm kev hloov pauv uas piav qhia txog kev hloov pauv hauv ib qho nucleotide ntawm DNA, xws li cov nucleotide hloov mus rau lwm nucleotide, lossis cov nucleotide raug tshem tawm, lossis ib qho nucleotide tau muab tso rau hauv DNA uas ua rau DNA sib txawv ntawm cov noob caj noob ces ib txwm los yog tsiaj qus…
Yuav ua li cas piv txwv ntawm kev hloov pauv hloov pauv?
Cov ntsiab lus
- 4.1 Cancer.
- 4.2 Neurofibromatosis.
- 4.3 Sickle-cell anemia.
- 4.4 Tay–Sachs tus kab mob.
- 4.5 xim dig muag.
3 hom kev hloov pauv yog dab tsi?
Types of Mutations
Muaj peb hom DNA Mutations: base hloov, tshem tawm thiab ntxig.
Kev hloov pauv twg yog qhov hloov pauv?
Muaj ob hom kev hloov pauv: kev hloov pauv hloov pauv thiab hloov pauv hloov pauv. Kev hloov pauv tshwm sim thaum lub hauv paus pyrimidine (piv txwv li, thymine [T] lossis cytosine [C]) hloov pauv rau lwm lub hauv paus pyrimidine lossis thaum lub hauv paus purine (piv txwv li, adenine [A] lossis guanine [G]) hloov rau lwm lub hauv paus purine.
Kev hloov pauv ib qho piv txwv yog dab tsi?
Piv txwv: Sickle-Cell Anemia: Mob ntshav-cell anemia tej zaum yuav yog ib qho teeb meem rov qab los ntawm ib qho kev hloov pauv hauv cov noob uas ua rau hemoglobin, uas nqa oxygen hauv cov ntshav. Nquag, glutamic acid yog tsim nyob rau hauv cov saw, tab sis qhov hloov pauv ua rau valine yuav tsum tau ua ntawmqhov chaw ntawd xwb.
Pom zoo:
Dab tsi yog qhov hloov pauv thiab hloov pauv hloov pauv?
Point mutations hloov ib leeg nucleotide. Frameshift kev hloov pauv yog ntxiv lossis tshem tawm ntawm nucleotides uas ua rau muaj kev hloov pauv hauv kev nyeem ntawv. frameshift thiab point mutation yog dab tsi? Ib qho kev hloov pauv cuam tshuam rau ib khub hauv paus.
Qhov kev hloov pauv no puas yuav ua rau muaj kev hloov pauv hloov pauv?
Yog li, yog tias muaj kev hloov pauv, piv txwv li, kev ntxig lossis tshem tawm ntawm nucleotide, tshwm sim, qhov no tuaj yeem ua rau kev hloov pauv ntawm kev nyeem ntawv. Nws hloov tag nrho cov amino acid ib ntus. Cov kev hloov pauv no yog hu ua frameshift mutation (tseem hu ua kev nyeem ntawv hloov pauv, nyeem ntawv hloov pauv, lossis framing yuam kev).
Puas yog jurassic ntiaj teb hloov pauv hloov pauv hloov pauv?
Qee zaum, paub meej, koj yuav tau rov qab mus rau lub sijhawm dhau los - txuag manually, thiab feem ntau, raws li game's autosave yog… tsis zam txim - tab sis feem ntau ntawm cov lub sijhawm koj tuaj yeem khaws cov khoom thiab khaws cia nrog.
Qhov twg yog qhov kev hloov pauv hloov pauv hloov pauv?
Semiconservative replication piav qhia txog cov txheej txheem ntawm DNA replication nyob rau hauv tag nrho cov paub hlwb. DNA replication tshwm sim ntawm ntau lub hauv paus pib ntawm kev rov ua dua raws DNA qauv strand. Raws li DNA ob chav helix yog unwound by helicase, replication tshwm sim nyias ntawm txhua tus qauv strand nyob rau hauv antiparallel cov lus qhia.
Qhov kev hloov pauv twg yog xav tias yuav cuam tshuam los ntawm kev hloov pauv hloov pauv?
Dependent Variable Qhov sib txawv uas nyob ntawm lwm yam uas ntsuas. Cov kev hloov pauv no yuav tsum tau hloov pauv raws li qhov kev sim ua haujlwm ntawm tus kheej hloov pauv lossis hloov pauv. Nws yog cov nyhuv presumed. Qhov kev tshawb fawb hloov pauv twg yog qhov tshwm sim?
