Lapatinib hla cov ntshav-hlwb thaiv vim nws cov qauv me me. Lapatinib tau pom tias tiv thaiv kev loj hlob ntawm lub hlwb metastases nyob rau hauv mob cancer mis thaum ua ke los yog ib leeg.
Puas Kadcyla hla BBB?
Ib tus yam ntxwv tseem ceeb yog qhov tsis zoo li cov tshuaj tiv thaiv kab mob HER2 xws li Herceptin thiab Roche's Perjeta (pertuzumab) thiab Kadcyla (trastuzumab emtansine) nws hla cov ntshav hlwb teeb meem, yog li ua haujlwm hauv cov neeg mob uas cov qog tau kis los yog metastasis mus rau hauv nruab nrab lub paj hlwb.
Puas Herceptin hla BBB?
Txawm tias muaj txiaj ntsig zoo ntawm cov lus teb thiab tag nrho cov ciaj sia, ib feem peb ntawm cov neeg mob kho nrog trastuzumab txhim kho lub hlwb metastasis. Trastuzumab yog ib qho tshuaj tiv thaiv kab mob monoclonal uas muaj ntau hom tshuaj tiv thaiv kab mob uas ua rau lub cev muaj zog ntxiv ntawm HER2 receptor thiab tsis tau hla cov ntshav-hlwb teeb meem (BBB).
Puas pertuzumab hla ntshav-hlwb barrier?
Peb muaj cov tshuaj tiv thaiv kab mob monoclonal, xws li trastuzumab lossis pertuzumab, thiab peb paub tias lawv tsis hla cov ntshav-hlwb teeb meem.
mob qog noj ntshav tuaj yeem hla cov ntshav-hlwb pob?
Cov qog nqaij hlav cancer taug kev los ntawm cov hlab ntsha nws thiaj li colonize ib qho chaw vascular, los ntawm kev ua rau cov hlwb endothelial, los yog hla lub hlwb thaiv kom pib cov txheej txheem uas ua rau lub niche tsim nyob rau hauv lub hlwb parenchyma.
