Epidermal kev loj hlob yam yog ib qho protein uas txhawb kev loj hlob ntawm tes thiab sib txawv los ntawm kev khi rau nws cov receptor, EGFR. Tib neeg EGF yog 6-kDa thiab muaj 53 amino acid residues thiab peb intramolecular disulfide bonds.
Dab tsi yog qhov kev loj hlob ntawm epidermal siv rau?
Epidermal growth factor (EGF) yog ib qho mitogenic yam uas stimulates proliferation ntawm ntau hom hlwb, tshwj xeeb tshaj yog fibroblasts thiab epithelial hlwb. EGF activates EGF receptor (EGFR/ErbB), uas pib, tig, intracellular signaling.
Dab tsi ua rau muaj qhov tshwm sim ntawm epidermal loj hlob?
submaxillary gland thiab raum yog qhov tseem ceeb ntawm EGF ntau lawm. EGF/EGFR signaling txhawb embryonic txoj kev loj hlob thiab qia cell regeneration thiab tswj ion thauj.
Kuv tuaj yeem tau txais cov kab mob epidermal loj hlob nyob qhov twg?
Epidermal loj hlob tuaj yeem pom hauv zis, qaub ncaug, mis nyuj, kua muag, thiab ntshav ntshav. Nws tuaj yeem pom nyob rau hauv cov qog nqaij hlav submandibular, thiab cov qog parotid. Kev tsim tawm ntawm EGF tau pom tias yuav txhawb nqa los ntawm testosterone.
Dab tsi secretes epidermal loj hlob?
Epidermal growth factor (EGF) yog synthesized thiab secreted by mmmalian anterior pituitary cells. Nws txhawb nqa GH thiab prolactin (PRL) tso tawm, tab sis lub hauv paus chiv keeb ntawm EGF yog qhov tsis tau tshawb nrhiav.
