Thiotepa tau muab tshuaj intrathecally (IT) ntawm tag nrho cov koob tshuaj ntawm 10 mg cuam tshuam nrog 40 mg ntawm methylprednisolone txhua lub lim tiam kom txog rau thaum CNS cov lus teb lossis kab mob. Tus lej nruab nrab ntawm peb qhov kev txhaj tshuaj [ntau 1–8] tau ua rau txhua tus neeg mob.
Yuav ua li cas chemo tuaj yeem muab tso rau hauv lub cev?
Cov tshuaj khomob uas feem ntau muab rau hauv lub cev (nrog rau lub lumbar puncture) yog: methotrexate . cytarabine.
Vim li cas methotrexate muab intrathecally?
Methotrexate yog tshuaj khomob uas siv los kho qee yam mob qog noj ntshav thiab leukemia. Thaum muab intrathecally, nws tiv thaiv cov kab mob leukemia nkag mus rau hauv cov kua cerebrospinal (CSF) nyob ib ncig ntawm tus txha nraub qaum thiab hlwb. Nws kuj tseem siv los kho cov kab mob leukemia pom hauv CSF.
Ntau npaum li cas yog intrathecal methotrexate muab?
Kev kho mob, feem ntau, koj yuav tau txais ob koob tshuaj ib lub lis piam thawj zaug thiab tom qab ntawd ib lub lim tiam lossis ib hlis. Lub biologic rituximab, qee zaum ua ke nrog methotrexate, yog siv rau qee hom lymphoma.
Dab tsi yog qhov ntim siab tshaj plaws rau kev txhaj tshuaj intrathecal?
Lub ntim ntawm cov tshuaj intrathecal ranges ntawm 0.5ml txog 5ml. Cov tshuaj solubility hauv cov ntim me me tuaj yeem yog qhov nyuaj rau cov neeg ua haujlwm lipophilic.
