2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Protein synthesis ntawm ribosomes, uas yog, kev txhais lus ntawm nucleotide sib lawv liag ntawm mRNA rau hauv cov amino acid ib ntus ntawm cov protein, yog cov txheej txheem cyclic. Nyob rau hauv txhua puag ncig ntawm elongation, ob tRNA molecules ua ke nrog cov mRNA txav los ntawm ribosome nyob rau hauv ib tug multistep txheej txheem hu ua translocation.
Kev hloov pauv tshwm sim nyob qhov twg hauv cov protein synthesis?
Thaum lub sijhawm sib txuas cov protein, mRNA thiab tRNAs tau txav mus dhau ntawm ribosome los ntawm cov txheej txheem hloov pauv hloov pauv. Kev txav mus los ntawm tRNAs los ntawm qhov chaw A (aminoacyl) mus rau P (peptidyl) site mus rau E (tawm) qhov chaw yog ua ke nrog kev txav ntawm lawv cov codons cuam tshuam hauv mRNA.
Dab tsi ua kom yooj yim hloov pauv ntawm ribosome ntawm mRNA?
tRNA–mRNA translocation yog txhawb los ntawm elongation factor G (EF-G) ntawm tus nqi ntawm GTP hydrolysis. … EF-G pab txhawb kev tsim cov kev hloov ntawm lub ribosome thiab uncouples rov qab motions ntawm lub ribosomal subunits, tsim ib tug qhib conformation nyob rau hauv uas cov tRNAs tuaj yeem txav tau sai.
Puas ribosome txav thaum lub sijhawm hloov chaw?
Ribosome dynamics yog ib qho tseem ceeb tsis yog tsuas yog hauv kev hloov pauv, tab sis kuj tseem nyob rau hauv cov xwm txheej rov qab, xws li kev hloov pauv thiab hla, thiab kho kom haum rau cov tshuaj tua kab mob. Thaum lub sij hawm elongation theem ntawm kev txhais lus ribosome txav raws mRNA thaum synthesising nascent polypeptide.
Qhov twg cuam tshuam rau kev hloov pauv ntawm ribosome raws mRNA?
Kev hloov chaw yog catalyzed los ntawm an elongation factor (EF-G hauv Escherichia coli) thiab koom nrog kev txav mus los ntawm cov molecules loj (mRNA thiab ob tRNAs) nyob rau qhov ntev (∼ 50 Å) nyob rau hauv lub ribosome.
Pom zoo:
Thaum twg qhov kev hloov pauv hloov pauv tshwm sim?
Nws xav tias yuav pab nrog mRNA paub los ntawm ribosome thaum txhais lus. Kev hloov kho kuj tseem siv qhov chaw ntawm qhov kawg ntawm RNA cov ntawv sau tseg. Txog 3' kawg ntawm RNA saw 30-500 adenines ntxiv rau hauv qhov hu ua poly A tail. qhov hloov pauv hloov pauv hloov pauv nyob qhov twg?
Qhov twg yog qhov kev hloov pauv hloov pauv hloov pauv?
Semiconservative replication piav qhia txog cov txheej txheem ntawm DNA replication nyob rau hauv tag nrho cov paub hlwb. DNA replication tshwm sim ntawm ntau lub hauv paus pib ntawm kev rov ua dua raws DNA qauv strand. Raws li DNA ob chav helix yog unwound by helicase, replication tshwm sim nyias ntawm txhua tus qauv strand nyob rau hauv antiparallel cov lus qhia.
Qhov kev hloov pauv twg yog xav tias yuav cuam tshuam los ntawm kev hloov pauv hloov pauv?
Dependent Variable Qhov sib txawv uas nyob ntawm lwm yam uas ntsuas. Cov kev hloov pauv no yuav tsum tau hloov pauv raws li qhov kev sim ua haujlwm ntawm tus kheej hloov pauv lossis hloov pauv. Nws yog cov nyhuv presumed. Qhov kev tshawb fawb hloov pauv twg yog qhov tshwm sim?
Los ntawm kev hloov pauv hloov pauv hloov pauv?
Kev hloov pauv hloov pauv hloov pauv (TMA) yog qhov isothermal (tsis hloov pauv nucleic acid kub), ib leeg-tube nucleic acid amplification system siv ob lub enzymes, RNA polymerase thiab thim rov qab kev sau ntawv. … Cov txheej txheem no tuaj yeem siv los tsom rau RNA thiab DNA.
Thaum twg qhov kev hloov pauv hloov pauv tau tshwm sim?
Kev Tawm Tsam Kev Hloov Kho tau tshwm sim nyob rau lub sijhawm kwv yees tib lub sijhawm li Protestant Reformation, tiag tiag (raws li qee qhov chaw) pib sai sai ua ntej Martin Luther qhov kev txiav txim siab ntawm Ninety-tsib Cov Lus Qhia rau lub qhov rooj ntawm Tsev fuabtais Tsev fuabtais hauv1517.
