Disulfide daim ntawv cog lus tsim thiab isomerization yog catalyzed cov txheej txheem hauv ob qho tib si prokaryotes thiab eukaryotic kab mob, thiab cov enzymes lub luag haujlwm hu ua "disulfide bond (Dsb) enzymes" rau lawv lub peev xwm cuam tshuam. tsim thiab isomerization ntawm disulfide bonds.
Cov txuas hniav disulfide nyob qhov twg?
Disulfide daim ntawv cog lus feem ntau tshwm sim hauv lub endoplasmic reticulum los ntawm oxidation. Yog li no disulfide bonds feem ntau pom muaj nyob rau hauv extracellular, secreted thiab periplasmic proteins, txawm hais tias lawv muaj peev xwm kuj tsim nyob rau hauv cytoplasmic proteins nyob rau hauv tej yam kev mob ntawm oxidative kev nyuaj siab.
Puas yog amylase muaj cov txuas txuas disulfide?
Cytosolic enzymes nyiam tswj kom txo qis cysteine seem ntau dua li cov enzymes zais cia (4). Raws li qhov tshwm sim, nws tau raug pom zoo tias cov enzymes zais cia xws li α-amylases yuav ua kom ruaj khov los ntawm kev tswj xyuas cov txuas hniav disulfide (4).
Puas tag nrho cov proteins muaj cov txuas hniav disulfide?
Intramolecular disulfide bonds stabilize lub tertiary qauv ntawm cov proteins thaum thoise uas tshwm sim intermolecularly koom nrog hauv stabilizing quartenary qauv. Tsis yog tag nrho cov proteins muaj cov nyiaj disulfide.
Puas enzymes thiab substrates ua disulfide bonds?
Cov tshuaj tiv thaiv no ua rau sib xyaw- disulfide daim ntawv cog lus ntawm cov enzyme thiab nws cov substrate, uas tuaj yeem daws tau ob txoj hauv kev. … Nyob rau hauv txoj kev no, thiol-disulfide pauv cov tshuaj tiv thaiv catalyzedlos ntawm cov chav kawm ntawm cov enzymes no txhua tus ua tiav los ntawm disulfide-txuas nruab nrab ntawm cov enzyme thiab cov substrate.