Direct oral anticoagulants Direct oral anticoagulants Direct thrombin inhibitors (DTIs) yog ib hom tshuaj uas ua raws li cov tshuaj tiv thaiv coagulants (txhim ntshav txhaws) by ncaj qha inhibiting enzyme thrombin (factor IIa). Qee tus tau siv tshuaj kho mob, thaum lwm tus tab tom kho kho mob. https://en.wikipedia.org › wiki › Direct_thrombin_inhibitor
Direct thrombin inhibitor - Wikipedia
xws li dabigatran etexilate, rivaroxaban, apixaban, edoxaban, thiab betrixaban feem ntau cuam tshuam nrog cov ntshav los yog chromogenic coagulation kev soj ntsuamthiab tej zaum yuav ua rau cov txiaj ntsig tsis raug lossis ua rau qhov ntsuas tsis tau txhais tau.
Dab tsi suav nrog hauv kev ua haujlwm hypercoagulable?
Cov kev ntsuas cuam tshuam suav nrog ntau qhov kev txiav txim siab feem ntau ntawm cov khoom ua haujlwm hypercoagulable: Lupus anticoagulant (LA) panels, activated protein C tsis kam, protein C thiab protein S kev ua, kev ua haujlwm antithrombin, thiab cov kev ua haujlwm tshwj xeeb. Cov kev sim no yuav tsum tsis txhob ua rau cov neeg mob noj DOACS.
Thaum twg koj xav tau kev ua haujlwm hypercoagulable?
Kev kuaj yuav tsum tau ua yam tsawg kawg 4-6 lub lis piam tom qab mob thrombotic tshwm sim lossis tsis txuas ntxiv ntawm cov tshuaj tiv thaiv coagulant / thrombolyticsuav nrog warfarin, heparin, direct thrombin inhibitors (DTIs), ncaj qha factor Xa inhibitors, thiab fibrinolytic agents [1, 4, 5].
Koj ua li cas kuaj rau Hypercoagulation?
Testssiv los pab txheeb xyuas cov kab mob hypercoagulable uas tau tshwm sim muaj xws li:
- Kev kuaj caj ces, suav nrog qhov ua tau V Leiden (Activated protein C tsis kam) thiab prothrombin noob hloov (G20210A)
- Antithrombin kev ua haujlwm.
- Protein C ua haujlwm.
- Protein S ua haujlwm
- Kev yoo mov ntshav ntshav homocysteine ntau ntau.
Puas Hemophilia yog lub xeev hypercoagulable?
Thaum cov neeg muaj hemophilia muaj qhov nce ntshav, cov neeg uas muaj thrombophilia muaj qhov ua rau txhaws. Ib yam li hemophilia tshwm sim los ntawm qhov txawv txav ntawm cov ntshav txhaws, qee hom thrombophilia kuj tshwm sim los ntawm qhov txawv txav ntawm cov ntshav txhaws.
