2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Direct oral anticoagulants Direct oral anticoagulants Direct thrombin inhibitors (DTIs) yog ib hom tshuaj uas ua raws li cov tshuaj tiv thaiv coagulants (txhim ntshav txhaws) by ncaj qha inhibiting enzyme thrombin (factor IIa). Qee tus tau siv tshuaj kho mob, thaum lwm tus tab tom kho kho mob. https://en.wikipedia.org › wiki › Direct_thrombin_inhibitor
Direct thrombin inhibitor - Wikipedia
xws li dabigatran etexilate, rivaroxaban, apixaban, edoxaban, thiab betrixaban feem ntau cuam tshuam nrog cov ntshav los yog chromogenic coagulation kev soj ntsuamthiab tej zaum yuav ua rau cov txiaj ntsig tsis raug lossis ua rau qhov ntsuas tsis tau txhais tau.
Dab tsi suav nrog hauv kev ua haujlwm hypercoagulable?
Cov kev ntsuas cuam tshuam suav nrog ntau qhov kev txiav txim siab feem ntau ntawm cov khoom ua haujlwm hypercoagulable: Lupus anticoagulant (LA) panels, activated protein C tsis kam, protein C thiab protein S kev ua, kev ua haujlwm antithrombin, thiab cov kev ua haujlwm tshwj xeeb. Cov kev sim no yuav tsum tsis txhob ua rau cov neeg mob noj DOACS.
Thaum twg koj xav tau kev ua haujlwm hypercoagulable?
Kev kuaj yuav tsum tau ua yam tsawg kawg 4-6 lub lis piam tom qab mob thrombotic tshwm sim lossis tsis txuas ntxiv ntawm cov tshuaj tiv thaiv coagulant / thrombolyticsuav nrog warfarin, heparin, direct thrombin inhibitors (DTIs), ncaj qha factor Xa inhibitors, thiab fibrinolytic agents [1, 4, 5].
Koj ua li cas kuaj rau Hypercoagulation?
Testssiv los pab txheeb xyuas cov kab mob hypercoagulable uas tau tshwm sim muaj xws li:
- Kev kuaj caj ces, suav nrog qhov ua tau V Leiden (Activated protein C tsis kam) thiab prothrombin noob hloov (G20210A)
- Antithrombin kev ua haujlwm.
- Protein C ua haujlwm.
- Protein S ua haujlwm
- Kev yoo mov ntshav ntshav homocysteine ntau ntau.
Puas Hemophilia yog lub xeev hypercoagulable?
Thaum cov neeg muaj hemophilia muaj qhov nce ntshav, cov neeg uas muaj thrombophilia muaj qhov ua rau txhaws. Ib yam li hemophilia tshwm sim los ntawm qhov txawv txav ntawm cov ntshav txhaws, qee hom thrombophilia kuj tshwm sim los ntawm qhov txawv txav ntawm cov ntshav txhaws.
Pom zoo:
Puas muaj kev cuam tshuam cuam tshuam qhov ua rau?
Thaum ua rau muaj kev cuam tshuam thiab kev sib raug zoo tuaj yeem tshwm sim nyob rau tib lub sijhawm, kev sib raug zoo tsis txhais hais tias ua rau. Kev ua txhaum yog siv rau cov xwm txheej uas qhov kev txiav txim A ua rau qhov tshwm sim B.
Lub sijhawm cuam tshuam-driven io voj voog dab tsi ua rau muaj kev cuam tshuam?
CPU muaj cov kab thov cuam tshuam uas tau hnov tom qab txhua qhov kev qhia. Ib lub cuab yeej tswj hwm tsa qhov cuam tshuam los ntawm lees paub lub teeb liab ntawm kev cuam tshuam thov kab. CPU tom qab ntawd ua lub xeev txuag, thiab hloov kev tswj mus rau qhov cuam tshuam tus neeg ua haujlwm niaj hnub ntawm qhov chaw nyob ruaj khov hauv nco.
Puas muaj kev cuam tshuam lossis cuam tshuam?
Effected txhais tau hais tias coj los, coj los ua thaum siv los ua lus qhia. … Kev cuam tshuam tuaj yeem siv los ua cov lus qhia dhau los uas txhais tau tias cuam tshuam lossis hloov pauv. Nws kuj tseem tuaj yeem siv los ua ib qho lus hais rau lub npe uas tau cuam tshuam (qhov cuam tshuam lub cev).
Puas tsis cuam tshuam cuam tshuam txog kev ywj pheej?
Cov lus tsis sib xws thiab independent yuav raug siv sib hloov ua lus Askiv, tab sis lawv tsis yog lus piv txwv hauv lej. Independent random variables are uncorrelated, but uncorrelated random variables tsis yog ib txwm ywj siab. Puas yog qhov tsis muaj kev cuam tshuam ib txwm muaj kev ywj pheej?
Puas yog kev cuam tshuam thiab kev cuam tshuam?
Reflection cuam tshuam nrog kev hloov pauv ntawm nthwv dej thaum lawv dhia tawm ntawm qhov thaiv. Kev cuam tshuam ntawm nthwv dej cuam tshuam nrog kev hloov pauv ntawm cov nthwv dej thaum lawv dhau los ntawm ib qho nruab nrab mus rau lwm qhov.
