Base hloov pauv yog yam yooj yim tshaj plaws ntawm kev hloov pauv noob, thiab lawv koom nrog kev sib pauv ntawm ib qho nucleotide rau lwm tus thaum lub sij hawm DNA replication. Piv txwv li, thaum lub sij hawm replication, thymine nucleotide tej zaum yuav muab tso rau hauv qhov chaw ntawm guanine nucleotide.
4 hom kev hloov pauv yog dab tsi?
Summary
- Germline mutations tshwm sim hauv gametes. Somatic mutations tshwm sim nyob rau hauv lwm lub cev hlwb.
- Chromosomal alterations yog mutations uas hloov chromosome qauv.
- Point mutations hloov ib zaug nucleotide.
- Frameshift kev hloov pauv yog ntxiv lossis tshem tawm ntawm nucleotides uas ua rau muaj kev hloov pauv hauv kev nyeem ntawv.
hom kev hloov nucleotide dab tsi?
Muaj peb hom kev hloov DNA: pib hloov pauv, tshem tawm thiab ntxig. Ib qho kev hloov pauv yog hu ua qhov hloov pauv hloov pauv, nco qab qhov hloov pauv ntawm Glu --- Val uas ua rau mob qog noj ntshav. Point mutations yog hom kev hloov pauv ntau tshaj plaws thiab muaj ob hom.
Dab tsi yog hom kev hloov pauv hloov pauv?
Muaj ob hom kev hloov pauv: kev hloov pauv hloov pauv thiab hloov pauv hloov pauv.
piv txwv ntawm kev hloov pauv yog dab tsi?
Qhov kev hloov pauv no tuaj yeem: hloov codon rau ib qho uas encodes ib qho amino acid sib txawv thiab ua rau muaj kev hloov me me ntawm cov protein uas tsim tawm. Piv txwv li,sickle cell anemia yog tshwm sim los ntawm kev hloov pauv hauv beta-hemoglobin noob, uas hloov ib qho amino acid hauv cov protein tsim.
