Succinyl CoA yog catalytically hloov mus rau succinate (Fig. 13.9), CoA, thiab GTP siv ib qho enzyme succinyl CoA synthetase succinyl CoA synthetase Succinyl coenzyme A synthetase (SCS, kuj paub. as succinyl-CoA synthetase los yog succinate thiokinase los yog succinate-CoA ligase) yog an enzyme uas catalyzes cov tshuaj tiv thaiv rov qab ntawm succinyl-CoA rau succinate. https://en.wikipedia.org › Succinyl_coenzyme_A_synthetase
Succinyl coenzyme A synthetase - Wikipedia
. Succinyl CoA synthetase (EC 6.2. 1.5) stimulates lub hydrolysis ntawm succinyl CoA rau hauv succinate thiab ATP thiab yog li sawv cev rau ib qho tseem ceeb point ntawm substrate theem phosphorylation [2, 18].
Yuav ua li cas thaum succinyl-CoA hloov mus rau succinate?
Kev hloov pauv ntawm succinyl CoA rau hauv succinic acid cuam tshuam nrog kev tshem tawm ntawm CoA enzyme thiab cov kauj ruam tsim lub zog hauv daim ntawv GTP. Cov kauj ruam no tsim ATP hauv cov nroj tsuag.
Thaum succinyl-CoA hloov mus rau succinate Dab tsi yog 2 yam uas tsim tawm?
Succinyl CoA tau hloov mus rau succinate hauv cov tshuaj tiv thaiv catalyzed los ntawm enzyme succinyl-CoA synthetase. Cov tshuaj tiv thaiv no hloov inorganic phosphate, Pi, thiab GDP rau GTP thiab tseem tso tawm ib pab pawg SH-CoA. Kauj Ruam 6. Succinate hloov mus rau fumarate hauv cov tshuaj tiv thaiv catalyzed los ntawm succinate dehydrogenase.
YPuas yog succinyl-CoA rau succinate oxidation?
(6)Oxidation ntawm Succinate rau Fumarate Lub succinate tsim los ntawm succinyl-CoA is oxidized rau fumarate los ntawm flavoprotein succinate dehydrogenase (txoj cai).
Succinyl-CoA hloov mus rau propionate li cas?
Yog li, propionyl-CoA yog muab los ntawm catabolism ntawm lipids thiab cov proteins. Hauv ruminants, propionate feem ntau tau los ntawm cov kab mob fermentation hauv rumen. Propionyl-CoA hloov mus rau succinyl-CoA, uas yog oxidized los yog hloov mus rau cov piam thaj los ntawm txoj kev ntawm oxaloacetate thiab pyruvate(gluconeogenesis; Tshooj 15).
