2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Yog tias muaj ib qho qub thiab ib qho txawv txav ntawm ib qho chaw tshwj xeeb, raws li pom nyob rau hauv ib qho kab mob autosomal dominant cancer susceptibility disorder, poob ntawm ib txwm allele ua ib locus nrog noib txwm muaj nuj nqi.
LOH yog dabtsi?
Kev poob ntawm heterozygosity (LOH) yog ib qho xwm txheej tshwm sim hauv caj ces hauv kev txhim kho mob qog noj ntshav, thiab paub tias muaj kev koom tes hauv kev poob ntawm cov tsiaj qus-hom alleles hauv ntau yam mob qog noj ntshav..
LOH ua rau mob qog noj ntshav li cas?
Kev poob ntawm heterozygosity (LOH) yog hais txoghom kev hloov pauv caj ces thaum lub sijhawm uas muaj qhov poob ntawm ib qho qauv ntawm cov noob lossis ib pawg ntawm cov noob. Qee zaum, kev poob ntawm heterozygosity tuaj yeem ua rau muaj mob qog noj ntshav.
Koj ua li cas txiav txim siab heterozygosity poob?
Kev poob ntawm heterozygosity tuaj yeem txheeb pom hauv cov qog nqaij hlav los ntawm ceeb toom qhov muaj heterozygosity ntawm cov caj ces hauv cov kab mob hauv cov kab mob DNA, thiab tsis muaj heterozygosity ntawm qhov chaw nyob hauv cov qog nqaij hlav. cells.
LOH tshwm sim qhov twg?
LOH tshwm sim thaum kab mob qog noj ntshav uas yog keeb kwm heterozygous ntawm ib qho chaw poob ib qho ntawm nws ob lub alleles ntawm qhov ntawdlocus, los ntawm kev tshem tawm ntawm ib qho allele (copy-loss LOH), lossis los ntawm kev tshem tawm ntawm ib qho allele nrog rau qhov sib npaug ntawm cov allele (copy-neutral LOH).
Pom zoo:
Thaum kev poob nyiaj poob haujlwm ib txwm yuav saib?
Thaum muaj kev lag luam poob qis, ib tus yuav pom ntau zaus: tus nqi poob haujlwm yuav nce ntxiv thaum cov khoom lag luam tag nrho poob. Thaum cov kws lag luam ntsuas kev lag luam loj hlob, lawv feem ntau siv: GDP tiag. Yuav ua li cas thaum muaj kev poob nyiaj txiag?
Dab tsi yog kev xav ntawm autonomists dab tsi yog qhov kev xav ntawm kev zoo nkauj ntawm kev coj ncaj ncees?
Kev lig kev cai, muaj ob txoj haujlwm tawm tsam kev xav txog kev coj ua raws li kev cai lij choj ntawm kev ntsuas kev ncaj ncees ntawm kev kos duab: 'kev coj ncaj ncees kev ncaj ncees Ethics lossis kev coj ncaj ncees yog ib ceg ntawm kev xav uas "
Qhov twg yog qhov kev txiav txim siab rau kev tsis lees paub thiab rau kev ua kom muaj kev tawm tsam ntawm kev tawm tsam?
Kev qhuab ntuas tau siv los ntawm cov thawj coj loj hauv cov tub rog Romanrau txim rau cov koom haum lossis pab pawg loj ua txhaum cai, xws li kev ua phem, kev tawm tsam, kev tawm tsam, thiab kev tsis ncaj ncees, thiab rau lub pacification ntawm rebellious legions.
Cov neeg ua haujlwm poob siab puas yog ib feem ntawm tus nqi poob haujlwm?
Vim tias cov neeg ua haujlwm poob siab tsis nquag nrhiav haujlwm, lawv suav tias yog cov neeg tsis koom nrog hauv kev ua lag luam-uas yog, lawv yog tsis suav tias poob haujlwm lossis tsis suav nrog lub zog ua haujlwm. Vim li cas cov neeg ua haujlwm poob siab tsis suav nrog tus nqi poob haujlwm?
Thaum poob ntawm heterozygosity tshwm sim?
Yog muaj ib qho qub thiab ib qho txawv txav ntawm ib qho chaw tshwj xeeb, raws li tau pom nyob rau hauv ib qho kev cuam tshuam ntawm autosomal dominant cancer susceptibility disorder, poob ntawm ib txwm allele ua ib qho chaw. tsis muaj kev ua haujlwm li qub.
