Feem ntau, neomycin yog siv hauv kev sim ntawm cov hlwb prokaryotic, thaum G418 yog siv hauv kev sim eukaryotic. Kanamycin yog ib qho tshuaj tua kab mob aminoglycoside uas ua haujlwm los ntawm inhibiting translocation ntawm ribosome uas ua rau mistranslation.
Yuav tshuaj tua kab mob dab tsi yog kanamycin?
Kanamycin belongs rau chav kawm ntawm cov tshuaj hu ua aminoglycoside tshuaj tua kab mob. Nws ua haujlwm los ntawm kev tua kab mob lossis tiv thaiv lawv txoj kev loj hlob.
Puas yog tetracycline thiab kanamycin tib yam?
Kanamycin sib cuam tshuam nrog 30S ribosomal subunit ua rau muaj kev hloov pauv tsis zoo thiab tiv thaiv kev hloov pauv thaum lub sijhawm sib xyaw protein [27, 28], thaum tetracyclines khi rau 16S ib feem ntawm 30S ribosomal subunit thiab tiv thaiv cov amino-acyl tRNA mus txuas rau ntawm A-site ntawm mRNA-ribosome complex, …
Cov tshuaj tua kab mob dab tsi uas kanamycin poob qis?
Kanamycin thiab amikacin
ob leeg kanamycin (t½ 2–4 h) thiab amikacin (t½ 2– 4 h) yog cov tshuaj tua kab mob ntawm aminoglycoside chav kawm, muaj txiaj ntsig rau cov neeg mob uas tsis kam tiv thaiv streptomycin.
Neomycin resistance gene yog dab tsi?
Neo (neomycin-resistance) gene ntawm transposon Tn5 encodes cov enzyme neomycin phosphotransferase II (EC 2.7. 1.95), uas confers resistance rau ntau yam aminoglycoside tshuaj tua kab mob, suav nrog kanamycin thiab G418.
