The sickle-cell allele yog dav paub tias yog ib qho txawv txav uas ua rau cov qe ntshav liab deformed rau hauv cov kab mob thaum deoxygenated hauv AS heterozygotes, uas A qhia tias tsis yog. -mutant daim ntawv ntawm β-globin noob, thiab tseem muab kev tiv thaiv rau malaria hauv AS heterozygotes.
Vim li cas cov neeg mob mob khaub thuas tiv taus malaria?
Thaum kev hloov pauv caj ces hauv beta globin noob tsim cov kab mob hemoglobin (HbS) ua rau muaj mob vascular hnyav uas tuaj yeem ua rau tuag ntxov rau cov tib neeg uas muaj homozygous (SS) rau kev hloov pauv, hauv nws daim ntawv heterozygous (AS), nws ib feem tiv thaiv kab mob npaws hnyav tshwm sim los ntawm P.
Puas heterozygotes tiv taus malaria?
Qhov muaj cov mutant hemoglobin hauv heterozygotes cuam tshuam nrog tus kab mob malarial parasite lub neej voj voog. Heterozygotes yog yog li no tiv taus ntau duacov teebmeem cuam tshuam ntawm malaria dua li homozygotes ib txwm.
Heterozygous resistant rau malaria yog dab tsi?
Sickle cell, S los yog βS los yog HbS Cov kab mob-cell allele yog dav paub tias muaj ntau yam. uas ua rau cov qe ntshav liab deformed mus rau hauv ib tug mob mob thaum deoxygenated nyob rau hauv AS heterozygotes, nyob rau hauv uas A qhia cov non-mutant daim ntawv ntawm β-globin noob, thiab kuj muab kev tiv thaiv rau malaria nyob rau hauv AS heterozygotes.
Yuav ua li cas tiv thaiv malaria hauv heterozygote?
Tus yam ntxwv zoo tshaj plaws ntawm tib neeg caj cespolymorphism txuam nrog malaria ua rau mob hemoglobin (HbS). Qhov ntau ntawm HbS nyob rau hauv sub-Saharan Africa thiab qee qhov chaw sov sov yog yuav luag vim muaj kev tiv thaiv malaria uas them rau heterozygotes [1–3, 5].
