2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Alpha-1-antitrypsin (AAT) yog ib qho protein uas tsim nyob rau hauv lub siabuas tiv thaiv lub cev cov ntaub so ntswg los ntawm kev puas tsuaj los ntawm cov kab mob tawm tsam los ntawm nws lub cev tiv thaiv kab mob.
Dab tsi ua rau alpha1 antitrypsin?
Alpha-1-antitrypsin yog tsim los ntawm tib neeg neutrophil granulocytesthiab lawv cov precursors thiab liberated thaum granule exocytosis.
Cov hlwb twg tsim alpha-1 antitrypsin hauv ntsws?
Alpha-1 antitrypsin (AAT) yog lub ntsiab proteinase inhibitor hauv lub ntsws. Nws yog tsim feem ntau los ntawm hepatocyteslos ntawm qhov uas nws tau zais rau hauv cov ntshav. Tom qab ntawd nws kis mus rau hauv lub ntsws qhov chaw uas nws ua raws li lub ntsiab inhibitor ntawm neutrophil elastase [1, 2].
Puas yog Alpha-1 antitrypsin tsim hauv daim siab?
Alpha-1-antitrypsin (AAt) yog ib qho serine protease inhibitor tsim feem ntau hauv daim siab. AAt deficiency, uas cuam tshuam rau cov txiv neej thiab poj niam sib npaug, tau txais los ntawm autosomal codominant zam thiab feem ntau ua rau mob siab, kab mob ntsws lossis ob qho tib si.
Thaum twg Alpha-1 antitrypsin deficiency tshwm sim?
Cov neeg muaj alpha-1 antitrypsin deficiency feem ntau tsim thawj cov tsos mob thiab cov tsos mob ntawm tus kab mob ntsws nruab nrab hnub nyoog 25 txog 50. Cov tsos mob ntxov tshaj plaws yog ua tsis taus pa tom qab ua haujlwm me me, txo qis kev tawm dag zog, thiab hawb pob.
Pom zoo:
Pom alpha helices nyob qhov twg?
Lub α-helix yog ib sab tes xis helix nrog cov peptide bonds nyob rau sab hauv thiab sab saw txuas sab nraud. Nws yog stabilized los ntawm cov tsis tu ncua tsim ntawm hydrogen bonds thaum uas tig mus rau lub axis ntawm lub helix; lawv raug tsim los ntawm cov amino thiab carbonyl pawg ntawm txhua plaub peptide daim ntawv cog lus.
Kev tsis ncaj ncees nyob qhov twg yog qhov hem rau kev ncaj ncees nyob txhua qhov chaw?
Martin Luther King tau hais tias: “Kev tsis ncaj ncees nyob txhua qhov chaw yog kev hem thawj rau kev ncaj ncees nyob txhua qhov chaw. Peb raug ntes nyob rau hauv ib tug inescapable network ntawm kev sib nrig sib pab, khi nyob rau hauv ib lub tsoos tsho ntawm txoj hmoo.
Qhov twg yog qhov tsis txaus ntseeg nyob qhov twg?
Yuav muaj ob lub cev tsis zoo nyob rau hauv lub midbrain. Lawv yog symmetrically positioned, ib tug nyob rau ntawm ob sab ntawm lub midline ntawm lub hlwb, thiab lawv tsim ob lub pob nyob rau hauv lub posterior nto ntawm lub paj hlwb nyob rau hauv qab ntawm lub superior colliculi.
Qhov twg tag nrho cov nqi hluav taws xob nyob ntawm qhov kev siv nyiaj siab tshaj plaws yog qhov twg?
marginal utility is zero. Tag nrho cov nqi hluav taws xob yog siab tshaj thaum marginal utility yog xoom. Qhov no yog vim muaj ntau txoj cai ntawm kev txo qis marginal utility uas hais tias tus neeg siv khoom noj ntau thiab ntau qhov zoo, qhov ntxiv rau tag nrho cov nqi hluav taws xob poob.
Puas yog alpha ib antitrypsin tsis muaj peev xwm tshwm sim?
Tus mob no tau txais los ntawm an autosomal codominant qauv. Codominance txhais tau hais tias ob qhov sib txawv ntawm cov noob tuaj yeem ua kom nquag plias (qhia), thiab ob qho tib si pab txhawb rau cov noob caj noob ces. Cov feem ntau version (allele) ntawm SERPINA1 noob, hu ua M, tsim ib txwm theem ntawm alpha-1 antitrypsin.
