2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Metabolism ntawm carcinogens tshwm sim hauv ntau cov ntaub so ntswg thoob plaws lub cev (ADMET Screen). … Nws yog dav ntseeg tias txoj hauv kev tseem ceeb hauv metabolic cuam tshuam nrog oxidation ntawm benzo[a]pyrene los ntawm cytochrome P450 (P450) rau ib qho epoxide.
Cov kab mob carcinogens ua haujlwm hauv koj lub cev li cas?
A carcinogen yog ib yam tus neeg muaj peev xwm ua rau mob qog noj ntshav rau tib neeg. Carcinogens tej zaum yuav yog ntuj, xws li aflatoxin, uas yog tsim los ntawm ib tug fungus thiab tej zaum kuj pom nyob rau hauv khaws cia nplej, los yog manmade, xws li asbestos los yog haus luam yeeb. Carcinogens ua haujlwm los ntawm kev cuam tshuam nrog lub cell DNA thiab inducing genetic mutations.
Cov kab mob carcinogens piav qhia dab tsi?
Ib yam mob qog noj ntshav ib yam uas ua rau koj mob qog noj ntshav. Tej zaum nws yuav yog ib yam khoom nyob rau hauv cov huab cua, ib yam khoom uas koj siv, los yog ib tug tshuaj nyob rau hauv cov zaub mov thiab dej qab zib.
Yuav ua li cas yog carcinogen?
Ntau cov carcinogens raug suav hais tias yog procarcinogens uas yuav tsum tau metabolic ua kom tawm dag zoglawv cov teebmeem genotoxic (4). Oxidative activation ntawm carcinogens los ntawm P450 enzymes ua rau tsim cov electrophilic reactive intermediates uas tuaj yeem khi rau DNA, ua rau cov DNA adducts uas yuav ua rau muaj kev hloov pauv (5)..
Dab tsi yog carcinogens thiab lawv cuam tshuam DNA li cas?
Carcinogens yog cov khoom uas ua rau muaj kev hloov pauv hauv DNA uas ua rau kev loj hlob ntawm cov qog nqaij hlav cancer. Carcinogens tuaj yeem raug cais raws li lub cev carcinogens, xws liRaws li ionizing hluav taws xob los yog ultraviolet lub teeb, los yog tshuaj carcinogens, xws li asbestos los yog cov khoom ntawm cov luam yeeb.
Pom zoo:
Nyob rau hauv angiosperms pollen yog tsim nyob rau hauv anthers ib feem ntawm?
Nyob rau hauv angiosperms, paj ntoos yog tsim los ntawm anthers ntawm the stamens hauv paj. Hauv gymnosperms, nws yog tsim nyob rau hauv microsporophylls ntawm microstrobili (txiv neej paj ntoos cones). Pollen muaj ib los yog ntau tshaj cov noob qoob loo thiab ib lub qe qe.
Yuav ua li cas txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau pom kev pom?
Txawm li cas los xij, corneal collagen cross-linking - cov txheej txheem qib siab tau pom zoo los ntawm US Food and Drug Administration (FDA) hauv xyoo 2016 - tuaj yeem txhim kho qhov pom kev hauv cov neeg mob txhua hnub nyoog. Corneal collagen cross-linking (CXL) tsis yog kho rau keratoconus, tab sis nws tuaj yeem pab tiv thaiv tus mob kom tsis txhob mob hnyav.
Yuav ua li cas txhawm rau txheeb xyuas qhov tsis zoo ntawm cov metabolism hauv yug?
Qhov kev kuaj pom tseeb tau tsim los ntawm daim siab biopsy lossis autopsy. Cov me nyuam mos feem ntau cuam tshuam rau qhov teeb meem thaum lub sij hawm ntxov ntawm lub neej. Koj ua li cas kuaj rau hauv yug tsis ua haujlwm ntawm cov metabolism?
Leej twg detering nyob rau hauv tag nrho cov nyob ntsiag to nyob rau sab hnub poob pem hauv ntej?
Detering yog tus neeg ua liaj ua teb los ntawm Txhua Tus Neeg Tsis Txaus Siabntawm Sab Hnub Poob los ntawm Erich Maria Remarque. Nws muaj siab mos siab muag, tshwj xeeb tshaj yog thaum nws los txog rau nees. Nws muaj kev kub ntxhov loj heev thaum nws hnov cov nees quaj thiab txawm sim tua lawv kom kawg lawv txoj kev txom nyem.
Nyob rau hauv lub cev ntawm tus txiv neej aqueduct ntawm sylvius tshwm sim nyob rau hauv?
Lub ventricles muaj plaub qhov khoob, cov kua dej puv hauv lub hlwb. … Nws txuas nrog lub paj hlwb aqueduct lossis aqueduct ntawm Sylvius hauv qhov nruab nrab ntawm lub hlwbrau plaub lub ventricle hauv pons thiab medulla. Lub aqueduct ntawm Sylvius nyob qhov twg?
