Yog li txawm tias theca hlwb tsis muaj FSH receptors , txawm li cas los xij, lawv txawm teb tsis ncaj rau FSH nrog nce ntau lawm ntawm androgens xav tau los ntawm granulosa hlwb granulosa hlwb Ib granulosa cell lossis follicular cell yog a somatic cell ntawm kev sib deev qaum uas yog ze rau cov poj niam gamete (hu ua oocyte lossis qe) hauv zes qe menyuam ntawm cov tsiaj. https://en.wikipedia.org › wiki › Granulosa_cell
Granulosa cell - Wikipedia
rau estrogen secretion.
Puas FSH ua rau lub hlwb?
LH thiab FSH ua txhawm rau txhawb nqa theca cellthiab granulosa cell sib txawv, raws li, hauv kev loj hlob antral follicles. LH activates LH receptor (LHR / LHCGR) hauv theca hlwb, ua rau muaj zog steroidogenesis (Cyp11a1, Cyp17a1) thiab androgen ntau lawm.
Pob theca cells qhia FSH receptors?
Nyob hauv theca hlwb, luteinizing hormone receptor (LHR) qhia tau raug sau tseg los ntawm lawv cov tsos. Hauv granulosa hlwb, follicle-stimulating hormone (FSH) stimulation yog tseem ceeb rau LHR qhia. … Tom qab ovulation, LHR qhia tau nce ntxiv mus rau luteinization.
FSH receptors nyob qhov twg?
Follicle-stimulating hormone (FSH), pituitary glycoprotein hormone, yog ib qho tseem ceeb ntawm cov endocrine axis uas tswj kev ua haujlwm ntawm gonadal thiab fertility. Txhawm rau xa nws cov teeb liab, FSH yuav tsum khi rau nws cov receptor(FSHR) nyob rau ntawm Sertoli hlwb ntawm testis thiab granulosa hlwb ntawm zes qe menyuam.
Cov receptors dab tsi ua rau lub hlwb muaj?
Theca hlwb muaj cov ntshav capillary ncaj qha thiab qhia cov qib siab ntawm LDL receptors, thiab qib siab ntawm P450scc thiab P450c17. Theca cells yog li tuaj yeem ua rau metabolize 21 carbon pregnenolone mus rau 19 carbon androstenedione, tab sis tsis muaj aromatase, thiab li no tsis tuaj yeem tsim cov tshuaj estrogen.
