Cimetidine tau pom tias inhibit lub siab microsomal metabolism ntawm benzodiazepines diazepam thiab chlordiazepoxide, ua rau muaj kev nce hauv ib nrab-lub neej thiab txo qhov kev tshem tawm ntawm ob cov tshuaj no.
Cov tshuaj twg cuam tshuam nrog chlordiazepoxide?
Qee yam khoom uas yuav cuam tshuam nrog cov tshuaj no suav nrog: antacids, qee yam tshuaj tiv thaiv kev nyuaj siab (xws li, fluoxetine, fluvoxamine, nefazodone), cimetidine, clozapine, digoxin, disulfiram, kava, sodium oxybate.
chlordiazepoxide metabolized li cas?
Chlordiazepoxide yog metabolized rau cov metabolites ntev hauv lub siab rau cov metabolite nordiazepam (desmethyldiazepam)thiab kev tshem tawm ntawm cov tshuaj txo qis hauv cov neeg laus thiab cov neeg mob. kab mob siab.
Yuav ua li cas yog lub tshuab ua haujlwm rau chlordiazepoxide?
Chlordiazepoxide binds rau stereospecific benzodiazepine (BZD) khi qhov chaw ntawm GABA (A) receptor complexes ntawm ntau qhov chaw nyob rau hauv lub hauv paus paj hlwb, suav nrog limbic system thiab reticular tsim. Qhov no ua rau muaj kev sib txuas ntxiv ntawm inhibitory neurotransmitter GABA rau GABA(A) receptor.
Cov tshuaj twg yog chlordiazepoxide?
Chlordiazepoxide yog siv los txo kev ntxhov siab thiab tswj kev ntxhov siab los ntawm kev tshem tawm cawv. Chlordiazepoxide yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu uabenzodiazepines.