Zoo li inbred nas hom, outbred nas stocks muaj lub ntsiab lus txhais: " ib tus neeg kaw (rau tsawg kawg yog plaub tiam) ntawm cov tsiaj txhu sib txawv uas yog bred kom muaj ntau tshaj heterozygosity " 2. Lub hom phiaj ntawm kev tswj hwm cov khoom lag luam tawm feem ntau yog txhawm rau txo qis kev hloov caj ces.
Dab tsi yog qhov txawv ntawm cov nas inbred thiab outbred?
Txiv neej, muaj ob chav loj ntawm cov nas kuaj: inbred thiab outbred. Inbred nas yog homogeneous thiab muaj yog qhov sib txawv me ntsis lossis heterogeneity nyob rau hauv ib hom kab mob ntshiab. … Cov nas uas tau yug los yog bred tshwj xeeb los ua kom muaj ntau haiv neeg thiab heterozygosity hauv cov pejxeem.
Yuav ua li cas yog ib haiv neeg outbreed?
Lub Diversity Outbred (DO) pejxeem yog a heterogeneous stock derived los ntawm tib yim tus tsim hom raws li tusCollaborative Cross (CC) inbred hom. Genetically heterogeneous DO nas tso saib ntau yam phenotypes. … Cov kab mob CC inbred muab cov peev txheej rau kev ua haujlwm ywj pheej ntawm DO daim ntawv qhia cov txiaj ntsig.
nas inbred siv dab tsi?
Inbred strains ntawm nas thiab nas yog cov tsiaj tsis muaj nuj nqis rau kev kawm cov caj ces ntawm cov phenotypic variation. Lawv tau txais los ntawm cov kwv tij-viv ncaus mates rau ntau tshaj 20 tiam, yog li txhua tus neeg muaj tib lub genome (isogenic) thiab txhua tus neeg yog homozygous ntawm txhua qhov chaw.
yog dab tsicov nas lov?
Cov tsiaj nas tawm (piv txwv li, CD-1 outbred nas, Sprague-Dawley outbred nas) muaj zog, muaj txiaj ntsig thiab pheej yig los yuav, thiab tau siv dav hauv kev tshawb fawb [15, 16]. Lawv feem ntau yog khaws cia raws li kev yug me nyuam loj nyob rau hauv uas muaj kev sib hloov ntawm cov caj ces sib txawv.
