2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Malonate yog kev sib tw inhibitor ntawm enzyme succinate dehydrogenase: malonate khi rau qhov chaw nquag ntawm cov enzyme yam tsis muaj kev cuam tshuam, thiab yog li sib tw nrog succinate, ib txwm muaj substrate ntawm enzyme. … Cov tshuaj malonate decreases cellular respiration.
Malonate inhibit qhov tsim ntawm fumarate los ntawm succinate li cas?
Tus inhibitor muaj qhov zoo sib xws rau cov txheej txheem ib txwm muaj rau cov enzyme, thiab sib tw nrog nws rau qhov chaw nquag. … Ib qho piv txwv yooj yim ntawm qhov no suav nrog malonate ions inhibiting enzyme succinate dehydrogenase. Qhov no enzyme catalyses hloov pauv ntawm succinate ions rau fumarate ions.
malonate inhibit SDH li cas?
Malonate, kev sib tw inhibitor ntawm SDH, kuj tau pom tias tsim cov poov tshuaj tam sim no ua rau mitochondrial matrix o (ib qho txiaj ntsig ntawm mitochondrial K ATPchannel ua haujlwm) thiab yog inhibited los ntawm ATP thiab 5-HD (20). Tsis tas li ntawd, kev sib txuas ntawm caj ces ntawm KATP channel thiab SDH tau thov (21).
Lub xub ntiag ntawm malonate cuam tshuam li cas cov tshuaj tiv thaiv nrog succinate dehydrogenase?
Malonate yog qhov thim rov qab inhibitor ntawm succinate dehydrogenase. Succinate dehydrogenase plays lub luag haujlwm tseem ceeb hauv lub voj voog tricarboxylic acid thiab ua ib feem ntawm complex II ntawm electron thauj saw. … Txhob nrog succinate thaiv covCov kab mob, vim nws cov txiaj ntsig ntawm succinate dehydrogenase (Greene li al. 1993).
Yuav ua li cas yog tias succinate dehydrogenase inhibited?
Ib qho tsis ua tiav ntawm succinate dehydrogenase kev ua haujlwm yuav cuam tshuam cov hluav taws xob ntws mus rau ob qho tib si ua pa txoj kab III thiab lub pas dej quinone, ua rau muaj kev ntxhov siab loj oxidative paub los txhawb cov qog tsim hauv tib neeg..
Pom zoo:
Lub sijhawm hloov pauv ntawm succinyl coa rau succinate?
Succinyl CoA yog catalytically hloov mus rau succinate (Fig. 13.9), CoA, thiab GTP siv ib qho enzyme succinyl CoA synthetase succinyl CoA synthetase Succinyl coenzyme A synthetase (SCS, kuj paub. as succinyl-CoA synthetase los yog succinate thiokinase los yog succinate-CoA ligase) yog an enzyme uas catalyzes cov tshuaj tiv thaiv rov qab ntawm succinyl-CoA rau succinate.
Dehydrogenase ua haujlwm li cas?
Dehydrogenases yog ib pawg ntawm cov tshuaj lom neeg lom neeg (enzymes) uas nruab nrab hauv cov tshuaj lom neeg biochemical tshem tawm hydrogen atoms [H] es tsis txhob oxygen [O] hauv nws cov tshuaj tiv thaiv oxido-txo. Nws yog ntau yam enzyme nyob rau hauv txoj kev ua pa ntawm txoj kev ua pa los yog cov hlau hloov hluav taws xob.
Puas yog botulinum toxin inhibits kev tso tawm ntawm acetylcholinesterase?
Botulinum toxin A inhibits acetylcholine tso los ntawm kab lis kev cai neurons hauv vitro. Hauv Vitro Cell Dev Biol Anim. botulinum toxin cuam tshuam li cas rau acetylcholine? Intramuscular tswj hwm ntawm botulinum toxin ua nyob rau ntawm lub neuromuscular hlws ris ua rau muscle tuag tes tuag taw los ntawm inhibiting tso tawm ntawm acetylcholine los ntawm presynaptic motor neurons.
Qhov twg fading cream inhibits tyrosinase?
Arbutin, ib qho tshuaj ntawm hydroquinone, yog ib yam khoom ntuj tsim thiab txo lossis inhibits melanin synthesis los ntawm inhibiting tyrosinase. YPuas azelaic acid inhibit tyrosinase? Downie hais tias azelaic acid kuj yog tyrosinase inhibitor, txhais tau tias nws tuaj yeem tiv thaiv hyperpigmentation vim nws cuam tshuam rau melanin ntau lawm.
Cov tshuaj twg inhibits cov metabolism ntawm chlordiazepoxide?
Cimetidine tau pom tias inhibit lub siab microsomal metabolism ntawm benzodiazepines diazepam thiab chlordiazepoxide, ua rau muaj kev nce hauv ib nrab-lub neej thiab txo qhov kev tshem tawm ntawm ob cov tshuaj no. Cov tshuaj twg cuam tshuam nrog chlordiazepoxide?
