Ib qho angiogenesis inhibitor yog ib yam khoom uas inhibits kev loj hlob ntawm cov hlab ntsha tshiab. Qee qhov angiogenesis inhibitors yog endogenous thiab ib feem ntawm lub cev tswj hwm thiab lwm tus tau txais exogenously los ntawm kev siv tshuaj lossis kev noj haus.
Lub hom phiaj tseem ceeb ntawm kev kho mob angiogenic yog dab tsi?
Cov tshuaj tiv thaiv angiogenic yog kho mob uas txwv cov qog los ntawm lawv cov hlab ntsha. Qhov no yuav ua rau qeeb ntawm kev loj hlob ntawm tus mob qog noj ntshav lossis qee zaum ua rau nws txo qis. Muaj ntau hom tshuaj tiv thaiv angiogenic. Cov no ua haujlwm sib txawv.
Yuav ua li cas tiv thaiv kev kho mob angiogenic ua haujlwm?
Cov kws tshawb fawb tau tsim cov tshuaj hu ua angiogenesis inhibitors, lossis kev kho mob los tiv thaiv angiogenic, txhawm rau cuam tshuam txoj kev loj hlob . Cov tshuaj no tshawb nrhiav thiab khi lawv tus kheej rau VEGF molecules, uas txwv tsis pub lawv los ntawm kev ua kom cov receptors ntawm cov hlwb endothelial hauv cov hlab ntsha. Bevacizumab (Avastin®) ua haujlwm li no.
Kev kho antiangiogenic zoo npaum li cas?
Lus xaus. Kev kho mob los tiv thaiv angiogenic tuaj yeemua haujlwm zoo li qub ntawm cov qog vasculature thiab txo qis cov hlab ntsha loj hlob rau lub sijhawm, lub npe hu ua lub qhov rais normalization, thaum cov kev kho mob ntxiv xws li tshuaj tua kab mob thiab hluav taws xob ua tau zoo dua.
Lub ntsiab lus ntawm kev tiv thaiv angiogenic yog dab tsi?
(AN-tee-AN-jee-oh-JEH-neh-sis AY-jent) A tshuaj los yog tshuaj uas ua kom cov hlab ntsha tshiab los ntawmforming. Hauv kev kho mob qog noj ntshav, cov tshuaj antiangiogenesis tuaj yeem tiv thaiv kev loj hlob ntawm cov hlab ntsha tshiab uas cov qog yuav tsum loj hlob. Kuj hu ua angiogenesis inhibitor.
