Prontosil: thawj cov tshuaj sulfa yuav raug tshawb pom . Feem ntau ntawm keeb kwm kev txaus siab niaj hnub no. Qhov kev tshawb pom no tau tsim los ntawm tus kws kho mob German zoo thiab kws kho mob Gerhard Domagk Gerhard Domagk Nws pom cov sulfonamide Prontosil muaj txiaj ntsig zoo tiv thaiv kab mob streptococcus, thiab kho nws tus ntxhais nrog nws, cawm nws txoj kev txiav caj npab. Xyoo 1939, Domagk tau txais Nobel nqi zog hauv Tshuaj rau qhov kev tshawb pom no,thawj cov tshuaj tiv thaiv kab mob. https://en.wikipedia.org › wiki › Gerhard_Domagk
Gerhard Domagk - Wikipedia
(1895-1964).
Cov khoom xyaw nquag hauv prontosil yog dab tsi?
Tus thawj sulphonamide, sulphanilamide, yog lub hauv paus ntsiab lus tseem ceeb ntawm Prontosil, uas tuav ib qho chaw tshwj xeeb hauv cov tshuaj ua thawj tus neeg sawv cev los nthuav tawm dav-spectrum kev ua haujlwm tiv thaiv kab mob kab mob (saib Ch. 1).
Yuav ua li cas yog sulfa tshuaj?
tshuaj muaj sulfa muaj xws li:
- sulfonamide tshuaj tua kab mob, suav nrog sulfamethoxazole-trimethoprim (Bactrim, Septra) thiab erythromycin-sulfisoxazole (Eryzole, Pediazole)
- qee cov tshuaj noj ntshav qab zib, xws li glyburide (Diabeta, Glynase PresTabs)
prontosil kho dab tsi?
Prontosil yog thawj cov tshuaj kho tau zoo kab mob kab mob thiab thawj zaug ntawm ntau cov tshuaj sulfa-forerunners ntawm cov tshuaj tua kab mob. Qhov kev ua tiav no tau txais nws tus tsim Nobel nqi zog, uas cov tub ceev xwm Germanyuam nws tsis kam lees.
Dab tsi hloov prontosil?
Prontosil tau hloov pauv hauv kev kho mob los ntawm cov tshuaj tshiab sulfonamide, suav nrog sulfanilamide, sulfathiazole, sulfamethoxazole, thiab lwm yam.
