2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Cov tshuaj paclitaxel yog lipophilic hauv qhov xwm txheej thiab insoluble hauv dej. Nws daim ntawv tam sim no ua lag luam raws li kev txhaj tshuaj intravenous paclitaxel yog solubilized los ntawm kev siv Cremophor EL, uas yog cov nonionic surfactant thiab pab hauv micellar solubilization.
Dab tsi yog solubilizing agents?
Solubilization yog nce hauv solubility ntawm cov dej-soluble tsis zoo nrog cov neeg ua haujlwm saum npoo. Cov txheej txheem cuam tshuam nrog kev nkag mus (adsorbed lossis yaj) ntawm cov molecules hauv micelles thiab nyiam cov surfactants los tsim cov colloidal aggregations ntawm qhov tseem ceeb micelle concentration.
txhais li cas los ntawm micellar solubilization?
Micellar solubilization (solubilization) yog txheej txheem ntawm kev koom ua ke cov solubilizes (cov khoom uas ua rau solublization) rau hauv lossis mus rau micelles. Solublization yuav tshwm sim nyob rau hauv ib tug system uas muaj ib tug hnyav, ib tug koom haum colloid (ib tug colloid uas tsim micelles), thiab tsawg kawg yog ib tug lwm solubilization.
Lub luag haujlwm ntawm micellar solubilization yog dab tsi?
Lub Hom Phiaj: Micellar solubilization yog ib qho kev xaiv muaj zog rau kev ua kom cov tshuaj hydrophobic nyob rau hauv ib puag ncig aqueous. … Daim ntawv thov ntawm micelles hauv kev xa tshuaj, txhawm rau txo qis cov tshuaj degradation thiab poob, tiv thaiv kev mob tshwm sim, thiab ua kom cov tshuaj bioavailability, kuj tau nthuav tawm.
micelles tsim los ntawm dab tsi?
1.2. Micelles Structure. Micelles feem ntau yog tsim los ntawm amphiphilic molecules nyob rau hauv aqueous tovuas nws tus kheej sib sau ua ke rau hauv cov qauv uas muaj ob qho tib si hydrophobic thiab ib ntu hydrophilic (Tshooj 2) [13, 14, 15].
Pom zoo:
In saml twg hauv qab no sawv cev rau tus neeg siv kawg?
SAML 2.0 yog XML-raws li kev cai uas siv kev ruaj ntseg tokens uas muaj cov lus lees paub kom dhau cov ntaub ntawv hais txog a tus thawj tswj hwm (feem ntau yog tus neeg siv kawg) ntawm SAML txoj cai, hu ua Tus Muab Kev Pab Cuam, thiab tus neeg siv khoom SAML, hu ua Tus Muab Kev Pabcuam.
Ib qho ntawm cov hauv qab no yog tus neeg sawv cev cycloplegic?
Cycloplegic tshuaj feem ntau yog muscarinic receptor muscarinic receptor Cov tshuaj nrog muscarinic antagonist kev ua haujlwm tau dav siv hauv cov tshuaj, hauv kev kho mob plawv qis, zais zis ntau dhau, teeb meem ua pa xws li mob hawb pob thiab COPD, thiab cov teeb meem neurological xws li Parkinson's disease.
Dab tsi ntawm cov hauv qab no yog tus neeg sawv cev keratolytic?
Qhov no ua haujlwm txhawm rau txhim kho daim tawv nqaij kom muaj peev xwm ntawm cov dej noo, uas muaj txiaj ntsig zoo hauv kev kho cov tawv nqaij qhuav. Cov tshuaj no (keratolytics) suav nrog alkali (los ntawm o thiab hydrolysis ntawm daim tawv nqaij), salicylic acid, urea, lactic acid, allantoin, glycolic acid, thiab trichloroacetic acid.
Nyob rau hauv lub cev ntawm tus txiv neej aqueduct ntawm sylvius tshwm sim nyob rau hauv?
Lub ventricles muaj plaub qhov khoob, cov kua dej puv hauv lub hlwb. … Nws txuas nrog lub paj hlwb aqueduct lossis aqueduct ntawm Sylvius hauv qhov nruab nrab ntawm lub hlwbrau plaub lub ventricle hauv pons thiab medulla. Lub aqueduct ntawm Sylvius nyob qhov twg?
Qhov twg hauv qab no sawv cev rau lub tswv yim ntawm tus kheej saib iav?
Lub ntsej muag-iav tus kheej piav qhia txog tus txheej txheem uas tib neeg pib lawv lub siab ntawm tus kheej ntawm qhov lawv ntseeg lwm tus saib lawv. Kev siv kev sib raug zoo raws li hom "daim iav," tib neeg siv cov kev txiav txim siab uas lawv tau txais los ntawm lwm tus los ntsuas lawv tus kheej muaj nqis, qhov tseem ceeb, thiab tus cwj pwm.
