2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Nws yog ib qho qauv molecule uas muaj feem cuam tshuam nrog anthracene nrog ib qho ntawm cov pawg CH hauv nruab nrab hloov los ntawm nitrogen. Zoo li cov molecules pyridine thiab quinoline, acridine yog me ntsis yooj yim. Nws yog ib qho yuav luag tsis muaj xim, uas crystallizes hauv koob.
Puas yog acridine muaj cov qauv bicyclic?
Acridine yog polycyclic heteroarene uas yog anthracene nyob rau hauv uas ib qho ntawm lub hauv paus CH pawg tau hloov los ntawm nitrogen atom. Nws muaj lub luag haujlwm ua genotoxin. Nws yog mancude organic heterotricyclic niam txiv, polycyclic heteroarene thiab cov tswv cuab ntawm acridines.
Dab tsi yog tshuaj acridine ring system?
Mepacrine (quinacrine), tshuaj acridine-based antimalarial tshuaj, tau tshawb pom xyoo 1932, thiab tau siv thaum Ntiaj Teb Tsov Rog II (1939-45) vim tsis muaj chloroquine. Xyoo 1944, penicillin tau hloov kho acridine raws li tshuaj tua kab mob [1].
Puas yog acridine ib txiv kab ntxwv?
Acridine Txiv kab ntxwv yog cell-permeant nucleic acid khi dyeuas tawm cov fluorescence ntsuab thaum khi rau dsDNA thiab liab fluorescence thaum khi rau ssDNA lossis RNA. Cov yam ntxwv tshwj xeeb no ua rau acridine txiv kab ntxwv muaj txiaj ntsig rau kev tshawb fawb ntawm tes. Acridine txiv kab ntxwv kuj tau siv los ua lysosomal dye.
Hom mutagen twg yog acridine txiv kab ntxwv?
Acridine txiv kab ntxwv yog cell-permeable, uas tso cai rau cov xim tuaj yeem cuam tshuam nrog DNA los ntawm kev sib cuam tshuam, lossis RNA ntawm electrostatic attractions. Thaum khirau DNA, acridine txiv kab ntxwv zoo ib yam li spectrally rau cov organic compound hu ua fluorescein.
Pom zoo:
Dab tsi ntawm cov hauv qab no yog cov kua qaub uas muaj zog tshaj chloroacetic acid?
Yog li, los ntawm cov kev xaiv tau muab, trichloroacetic acid yuav yog cov kua qaub uas muaj zog tshaj plaws vim tias muaj peb chlorine atoms tam sim no ntawm tib cov pa roj carbon uas yuav cuam tshuam cov nqi tsis zoo tshaj plaws thiab ua rau Qhov ruaj khov tshaj plaws carboxylate ion.
Puas yog warheads muaj lub hauv paus qaub?
Tangy txiv hmab txiv ntoo, zoo li txiv qaub thiab txiv qaub, yog loaded nrog citric acid. Yog li yog Warheads, qhov twg nws muab qhov pib tawg ntawm qhov phem-nws-zoo qaub. Zoo li tag nrho cov kua qaub, citric acid yields hydrogen ions uas ua kom tus nplaig qaub saj receptors.
Puas yog cov kua dej nres lub hwj chim tswj cov kua dej?
Cov kua nplaum thiab lub hwj chim tswj cov kua dej yogob lub kua siv hauv lub tshuab hydraulic hauv cov tsheb niaj hnub, tab sis qhov zoo sib xws tsis mus deb tshaj qhov ntawd. Nres thiab lub hwj chim tswj cov kua dej tau tsim thiab ua kom zoo nyob rau ntau xyoo los ua haujlwm sib txawv hauv cov tsheb, thiab lawv tsis hloov pauv.
Puas yog hemiacetals ruaj khov hauv cov kua qaub?
Hemiacetals tuaj yeem ua ke hauv cov tshuaj yooj yim. Tab sis lawv tsis tuaj yeem hnov mob ntxiv los tsim ib qho acetal hauv kev daws teeb meem. … Cyclic hemiacetals yog tsim los ntawm cov suab thaj hauv cov kua dej. Lawv yog qhov ruaj khov txawm tias nyob rau hauv cov kua qaub me ntsis.
Cov ntsuas olfactory qhia li cas cov kua qaub thiab cov hauv paus?
Ib qho taw qhia olfactory ua haujlwm ntawm lub hauv paus ntsiab lus tias thaum muaj kua qaub lossis lub hauv paus ntxiv rau nws, ces cov ntxhiab tsw txawv tuaj yeem kuaj pom hauv cov hauv paus whereastsw tsw zoo ib yam hauv cov kua qaub. Qee yam tshuaj uas hloov nws cov ntxhiab hauv Acidic lossis nruab nrab nruab nrab.
