Cov nyom rau nitration ntawm aniline tau kov yeej los ntawm kev tiv thaiv ntawm cov amino pawg los ntawm acetylation. Cov acetyl pawg txo cov reactivity ntawm lub nplhaib thiab yog li nws oxidation tsis tshwm sim yooj yim nrog nitric acid HNO3.
Qhov twg reagent siv los tiv thaiv cov amino pawg thaum lub sij hawm nitration ntawm aniline?
SOCl2 / Pyridine.
Dab tsi yog qhov khoom kawg ntawm nitration ntawm aniline ua ntej tiv thaiv?
Vim li ntawd, thaum cov nitration ntawm aniline tau ua tiav, nws tsis tsuas yog muab cov khoom siv nitration tab sis kuj muaj qee cov khoom oxidation. Txawm li cas los xij, nyob rau hauv kev tswj hwm, yog tias cov nitration ntawm aniline tau ua tiav, cov khoom lag luam loj yogp-nitroaniline thiab m-nitroaniline.
Yuav ua li cas thaum aniline nkag mus rau nitration?
Thaum muaj nitration hauv aniline, cov Nitric Acid protonates aniline los tsim cov Anilinium ion. Tam sim no txij li thaum lub nitrogen atom tsis muaj ib tug khub rau conjugate, nws tsis muaj mesomeric nyhuv ntawm lub nplhaib, tab sis raws li nitrogen yog tam sim no protonated, nws muaj ib tug siab tsis zoo inductive nyhuv.
Vim li cas aniline tsim cov khoom lag luam meta ntawm nitration?
Cov pab pawg anilinium, tsis muaj ib khub electron dawb lawm (txuas nrog H^+), deactivates lub nplhaib uas muaj ntxhiab mus rau kev hloov pauv electrophilic, kuj anilinium ion uas yog cov lus qhia meta. Li no, nitration ntawm aniline muabmeta derivative nrog rau ortho thiab para.
