Cov txiaj ntsig: Ntau hom tshuaj kho ntau yam tau raug tshawb xyuas, xws li qog nqaij hlav, tua tus kheej, antiangiogenesis, inflammatory cytokine thiab micro-RNA noob. Kev nce qib tsis ntev los no txhawj xeeb cov kab mob tshiab, xws li cov kab mob oncolytic, thiab kev sib koom ua ke ntawm kev kho cov noob kab mob, kws khomob thiab kev kho hluav taws xob.
Dab tsi yog qhov kev txhim kho tsis ntev los no hauv kev kho noob 2021?
Nrog Gene Therapy, Cov kws tshawb fawb Tshuaj Opioid-Free Solution for Chronic Pain. Lub Peb Hlis 10, 2021 - Kev kho noob rau kev mob ntev tuaj yeem muab kev nyab xeeb dua, tsis muaj kev quav yeeb tshuaj rau opioids. Cov kws tshawb fawb tau tsim txoj kev kho tshiab, uas ua haujlwm los ntawm kev txwv ib ntus ntawm cov noob koom nrog kev hnov qab …
Tam sim no ntawm kev tshawb fawb noob caj noob ces yog dab tsi?
Gene therapy tuav cov lus cog tseg rau kev kho ntau yam kab mob, xws li mob qog noj ntshav, cystic fibrosis, kab mob plawv, ntshav qab zib, hemophilia thiab AIDS. Cov kws tshawb fawb tseem tab tom kawm yuav ua li cas thiab thaum twg siv cov tshuaj kho noob. Tam sim no, hauv Tebchaws Meskas, kev kho noob muaj tsuas yog ib feem ntawm kev sim tshuaj.
Yeeb yam tshiab yog dab tsi?
Cov kws tshawb fawb tab tom sim ntau txoj hauv kev rau kev kho noob, suav nrog: Hloov cov noob hloov pauv uas ua rau muaj kab mobnrog cov qauv zoo ntawm cov noob. Inactivating, los yog "knocking," ib tug mutated noob uas ua hauj lwm tsis zoo. Qhia cov noob tshiab rau hauv lub cev los pab tua kab mob.
Dab tsi yog qhov tshiab tshaj plawsgene kho cov tswv yim tab tom tsim?
Cov kws tshawb fawb tau tsim cov cuab yeej kho cov noob tshiab hu ua Retron Library Recombineering (RLR) uas tuaj yeem tsim ntau lab ntawm kev hloov pauv ib txhij, thiab 'barcodes' mutant kab mob hlwb kom cov tag nrho pas dej ua ke tuaj yeem tshuaj xyuas ib zaug.
