2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Reverse-transcriptase inhibitors yog ib chav kawm ntawm cov tshuaj tiv thaiv kab mob uas siv los kho tus kab mob HIV lossis AIDS, thiab qee kis kab mob siab B. RTIs inhibit kev ua haujlwm ntawm rov qab transcriptase, tus kab mob DNA polymerase uas xav tau rau kev rov ua dua ntawm HIV thiab lwm yam. retroviruses.
Yuav ua li cas thim rov qab transcriptase inhibitors ua haujlwm?
Nucleoside thim rov qab transcriptase inhibitors (NRTIs) thaiv kev thim rov qab transcriptase (tus kab mob HIV). HIV siv thim rov qab transcriptase los hloov nws RNA rau hauv DNA (reverse transcription). Blocking reverse transcriptase and reverse transcription tiv thaiv HIV los ntawm kev rov ua dua.
Dab tsi yog qhov thim rov qab transcriptase inhibitors piv txwv?
Thaum feem ntau teev nyob rau hauv kev txiav txim, NRTIs / NtRTIs yog nucleoside / nucleotide analogues ntawm cytidine, guanosine, thymidine thiab adenosine: Thymidine analogues: zidovudine (AZT) thiab stavudine (d4T) Cytidine analogues (ddC), lamivudine (3TC), thiab emtricitabine (FTC)
Cov tshuaj thim rov qab ua cov tshuaj transcriptase ua li cas?
Reverse transcriptase inhibitors yog nquag tawm tsam HIV, tus kab mob retrovirus. Cov tshuaj inhibit RNA virus replication los ntawm reversible inhibition ntawmtus kab mob HIV reverse transcriptase, uas thim rov qab transcribes tus kab mob RNA rau hauv DNA rau ntxig rau hauv tus tswv tsev DNA sib lawv liag (saib daim duab 51.6).
Cov tshuaj twg yog lub luag haujlwm rau inhibition of viral reverse transcriptase?
Management of HIV Infection
The NRTIs were thethawj chav kawm ntawm ARVs muaj rau kev kho mob HIV. NRTIs inhibit tus kab mob HIV rov qab transcriptase enzyme, uas yog lub luag haujlwm rau kev hloov pauv ntawm tus kab mob RNA rau hauv DNA.
Pom zoo:
Puas yog cov dab dab dab dab dab dab dab dab dab dab dab dab?
Myth: Ib tug dab tshos tsis yog neeg ncaj ncees yog tiasnws haum yog. Fact: Tu siab, qhov no yog ib lo lus tsis tseeb uas tau raug perpetuated los ntawm aversive trainers. Txawm hais tias haum rau lub caj dab kom zoo khawb rau hauv cov tawv nqaij rhiab nyob ib ncig ntawm lub caj dab, uas ua rau muaj kev puas tsuaj loj rau cov thyroid, esophagus, thiab trachea.
Qhov twg yog qhov laj thawj tseem ceeb rau kev thim rov qab / tig rov qab lub tswv yim?
Lub hom phiaj yog txo cov nqi, ua kom cov haujlwm ua haujlwm zoo, lossis ua kom cov nyiaj ntsuab ntws ruaj khov. Peb lub hom phiaj tseem ceeb ntawm kev thim rov qab yog: Txoj Cai Hloov Kho - Qhov no yog lub tswv yim tsim kho dua tshiab. Nws hu kom rov kho cov haujlwm kom tau nyiaj ntau dua lossis tau txais txiaj ntsig.
Cov tshuaj twg yog nucleoside thim rov qab transcriptase inhibitors?
Available NRTIs zidovudine (Retrovir) Ylamivudine (Epivir) abacavir sulfate (Ziagen) didanosine (Videx) delayed-tso didanosine (Videx EC) stavudine (Zerit) emtricitabine (Emtriva) tenofovir disoproxil fumarate (Viread) Dab tsi yog nucleoside thim rov qab transcriptase enzyme inhibitors?
Puas thim rov qab transcriptase inhibitors kho mob HIV?
HIV kho tsis tau, tab sis feem ntau tswj tau. Kev kho nrog nucleoside/nucleotide thim rov qab transcriptase inhibitors (NRTIs) yog ib txoj hauv kev los pab tiv thaiv tus kab mob los ntawm kev rov ua dua thiab tswj kev kis kab mob HIV. Puas thim rov qab transcriptase inhibitors kho HIV?
Puas yog thim rov qab transcriptase ib qho kev txwv enzyme?
Reverse transcriptase yog ib qho enzyme uas tsim los ntawm qee cov kab mob (retroviruses, uas khaws lawv cov ntaub ntawv caj ces li RNA tsis yog DNA), uas, raws li lub npe txhais, thim rov qab cov txheej txheem ntawm kev sau npe. Cov piv txwv ntawm kev txwv enzymes yog dab tsi?
