Nyob rau hauv cov neeg laus, ib qho mob hnyav ntawm ntau tshaj 150 mg / kg lossis 12 g ntawm acetaminophenyog suav tias yog tshuaj lom thiab ua rau muaj kev pheej hmoo siab ntawm daim siab puas. Hauv cov menyuam yaus, kev noj tshuaj hnyav ntawm 250 mg / kg lossis ntau dua ua rau muaj kev pheej hmoo loj rau acetaminophen-induced hepatotoxicity.
Puas yog acetaminophen ua rau mob hepatotoxicity?
Acetaminophen yog ib qho tshuaj uas tsis siv tshuaj kho mob thiab tshuaj tua kab mob rau qhov mob me me mus rau nruab nrab thiab kub taub hau. Tsis muaj teeb meem thaum noj tsawg, acetaminophen muaj peev xwm hepatotoxic ncaj qha thaum noj ntau dhauthiab tuaj yeem ua rau mob siab rau lub siab thiab tuag los ntawm lub siab tsis ua haujlwm.
Acetaminophen ntau npaum li cas rau lub siab?
Hauv cov neeg laus, qhov tsawg kawg nkaus koob tshuaj acetaminophen raws li kev noj ib zaug yog 7.5 txog 10 g;>150 mg / kg lossis 12 g ntawm acetaminophen hauv cov neeg laus yog suav tias yog tshuaj lom thiab ua rau muaj kev pheej hmoo siab ntawm daim siab puas.
Muaj pes tsawg mg ntawm acetaminophen yog tshuaj lom?
Cov neeg laus yuav tsum tsis txhob noj ntau dua 3,000 mg ntawm cov tshuaj acetaminophen ib hnub. Koj yuav tsum noj tsawg dua yog tias koj muaj hnub nyoog tshaj 65 xyoo. Kev noj ntau dua, tshwj xeeb tshaj yog 7, 000 mg lossis ntau dua, tuaj yeem ua rau muaj teeb meem ntau dhau.
Leej twg yog tus raug mob rau hepatotoxicity los ntawm koob tshuaj acetaminophen ntau tshaj?
20 Cov neeg mob hnub nyoog tshaj 40 xyoo uas tau noj ntau dhau ntawm APAP qhia txog kev pheej hmoo siab dua ntawm daim siab tsis ua haujlwm, hloov daim siab thiab tuag. 5 Feem ntau, APAPCov metabolism tshwm sim muaj hnub nyoog, nrog cov neeg mob laus ua rau muaj kev pheej hmoo siab ntawm hepatotoxicity tom qab mob hnyav dhau ntawm APAP dua li cov neeg mob.
