Cetirizine tsis tau metabolized hauv daim siab. Tsuas yog 8-10% yog metabolized los ntawm P450 cytochrome oxidase txoj kev. Qhov no yuav ua rau nws xaiv cov tshuaj rau cov neeg mob uas muaj kab mob siab lossis noj lwm yam tshuaj cuam tshuam rau cytochrome P450 enzyme system.
YPuas Zyrtec metabolized los ntawm ob lub raum?
Cetirizine yog tshem tawm feem ntau los ntawm lub raum tab sis kuj ua rau cov metabolism hauv lub siab rau qee yam. Cov neeg mob lub raum thiab / lossis kab mob siab tuaj yeem ua rau muaj kev pheej hmoo ntau dua los ntawm kev cuam tshuam los ntawm cetirizine vim txo cov tshuaj tshem tawm.
Puas tshuaj tiv thaiv kab mob metabolized los ntawm daim siab?
Hmoob H1 los yog H2 tshuaj tiv thaiv tau txais presystemic metabolism hauv daim siab ntawm cytochrome P-450. Raws li, kev txo qis ntawm cov tshuaj tiv thaiv antihistamine txo qis yog qhia rau cov neeg mob uas lub siab lossis lub raum tsis ua haujlwm.
Puas cetirizine muaj kev nyab xeeb rau daim siab?
Hepatotoxicity. Kev siv Cetirizine thiab levocetirizine feem ntau tsis cuam tshuam nrog lub siab enzyme nce, tab sis tau txuas rau qhov tsis tshua muaj tshwm sim ntawm kev mob siab rau daim siab.
Puas Zyrtec absorbed hauv plab?
Cetirizine yog nqus tau ntau thiab nrawm ntawm lub plab [15], ua rau muaj bioavailability siab thiab pib ua haujlwm sai [16].
