Phenylephrine feem ntau metabolised hauv lub plab phab ntsa thiab daim siab[1, 8]. Txoj hauv kev tseem ceeb ntawm cov metabolism yog sulphation thiab glucuronidation ntawm 3-hydroxyl pawg thiab oxidative deamination los ntawm monoamine oxidase rau 3-hydroxymandelic acid thiab 3-hydroxyphenylglycol.
Neosynephrine metabolized nyob qhov twg?
Qhov ncauj phenylephrine yog metabolized ntau los ntawm monoamine oxidase, ib qho enzyme uas muaj nyob rau ntawm mitochondrial membrane ntawm cov hlwb thoob plaws hauv lub cev.
Dab tsi receptor ua phenylephrine lub hom phiaj?
Phenylephrine yog siv dav vasopressor hauv chav ua haujlwm rau kev kho mob hypotension. Lub hom phiaj tseem ceeb ntawm kev sib txuas ntawm phenylephrine yog α-adrenergic receptor nrog rau siab tshaj plaws affinity rau α 1 - receptor.
YPuas yog phenylephrine yog ib qho sympathomimetic?
Phenylephrine yog ib qho sympathomimetic amine uas nquag siv los ua qhov ntswg decongestant.
Puas yog phenylephrine raug rau degradation los ntawm Mao hauv plab?
Synthetic tshuaj tsim los qhib adrenergic receptors, piv txwv li, phenylephrine, tau raug tsim los uas yog tiv taus degradation los ntawm enzyme thiab yog li muaj ib nrab neej ntev.
