Conjugated bilirubin tseem hu ua direct bilirubin vim nws reacts ncaj qha nrog cov reagent, thiab unconjugated bilirubin hu ua indirect vim nws yuav tsum tau solubilized ua ntej. Thaum haus cawv ntxiv rau hauv qhov kev sim, txawm li cas los xij, ob qho tib si cov ntawv ncaj qha thiab tsis ncaj qha cuam tshuam.
Dab tsi yog qhov txawv ntawm qhov ncaj qha thiab tag nrho bilirubin?
Feem ntau, koj yuav tau txais cov txiaj ntsig ncaj qha thiab tag nrho bilirubin. Cov txiaj ntsig zoo li qub rau kev kuaj tag nrho bilirubin yog 1.2 milligrams ib deciliter (mg / dL) rau cov neeg laus thiab feem ntau 1 mg / dL rau cov hnub nyoog qis dua 18. Cov txiaj ntsig zoo rau ncaj bilirubin feem ntau yog 0.3 mg / dL. Cov txiaj ntsig no yuav txawv me ntsis ntawm chav kuaj mus rau chav kuaj.
Puas yog daj daj los ntawm kev ncaj qha lossis tsis ncaj ntawm bilirubin?
ua rau ua rau mob ntshav qab zib jaundice suav nrog hemolysis thiab hematoma resorption, uas ua rau nce qib ntawm unconjugated (indirect) bilirubin. Cov kab mob intrahepatic tuaj yeem ua rau tsis sib haum xeeb lossis sib koom ua ke hyperbilirubinemia.
Qhov twg ntau dua ncaj qha lossis tsis ncaj bilirubin?
Indirect bilirubin tej zaum yuav siab dhau thaum lub siab tsis tuaj yeem ua haujlwm txaus (conjugated) bilirubin lossis thaum muaj qhov txawv txav ntawm cov qe ntshav liab (hemolysis). Lub caij no, ncaj qha bilirubin tuaj yeem siab dhau yog tias lub siab tsis tuaj yeem dhau ntawm bilirubin tom qab nws tau sib txuas.
Cov tshuaj tiv thaiv dab tsi txiav txim siab bilirubin?
Van den Bergh cov tshuaj tiv thaiv yog tshuaj tiv thaiv siv losntsuas qib bilirubin hauv cov ntshav. Tshwj xeeb tshaj yog, nws txiav txim siab tus nqi ntawm conjugated bilirubin hauv cov ntshav. Cov tshuaj tiv thaiv tsim azobilirubin. Lub hauv paus ntsiab lus: bilirubin reacts nrog diazotised sulphanilic acid los tsim cov xim liab azobilirubin.
