A frameshift mutation yog ib hom kev hloov pauv uas cuam tshuam nrog kev ntxig lossis tshem tawm ntawm nucleotide uas tus lej ntawm tus lej rho tawm tsis raug faib los ntawm peb.
Yuav ua li cas thaum lub nucleotide raug tshem tawm?
Piv txwv li, yog tias tsuas yog ib qho nucleotide raug tshem tawm ntawm qhov sib lawv liag, ces tag nrho cov codons suav nrog thiab tom qab kev hloov pauv yuav muaj kev cuam tshuam kev nyeem ntawv. Qhov no tuaj yeem ua rau muaj kev sib koom ua ke ntawm ntau cov amino acids tsis raug rau hauv cov protein.
hom kev hloov pauv yog kev hloov pauv li cas?
Kev tshem tawm. Kev rho tawm yog hom kev hloov pauv cuam tshuam nrog kev poob ntawm cov khoom siv caj ces. Nws tuaj yeem yog me me, suav nrog ib tus khub DNA uas ploj lawm, lossis loj, suav nrog ib daim chromosome.
hom kev hloov pauv twg tshwm sim thaum ib lub hauv paus raug tshem tawm?
Tsis muaj tseeb: Thaum qhov hloov pauv hauv paus ua rau nres codon thaum kawg txiav cov lus txhais thiab feem ntau yuav ua rau cov protein tsis ua haujlwm. Kev tshem tawm, ua rau a frameshift, tshwm sim thaum ib lossis ntau lub hauv paus khub ploj ntawm DNA (saib daim duab saum toj no).
Yuav ua li cas thaum nucleotide hloov pauv?
Kev hloov pauv tuaj yeem hloov pauv qhov zoo ntawm txoj hauv kev uas tej zaum yuav pab tau, xws li ua kom lub cev hloov mus rau nws ib puag ncig zoo dua. Qhov kev hloov pauv yooj yim tshaj plaws yog qhov hloov pauv hloov pauv. Qhov no tshwm sim thaum ib lub hauv paus nucleotide hloov rau lwm qhov hauv DNAsequence. Qhov kev hloov pauv tuaj yeem ua rau cov amino acid tsis raug tsim tawm.
