Hexamethonium, nicotinic acetylcholine receptor (nAchR) antagonist, feem ntau hu ua tus qauv ganglionic blocker ganglionic blocker Ib ganglionic blocker (los yog ganglioplegic) yog ib hom tshuaj uas inhibits kev sib kis ntawm preganglionic thiab postganglionic neurons nyob rau hauv lub autonomic paj hlwb, feem ntau los ntawm kev ua tus nicotinic receptor antagonist. … Qhov ntxeev ntawm ib tug ganglionic blocker yog hu ua ganglionic stimulant. https://en.wikipedia.org › wiki › Ganglionic_blocker
Ganglionic blocker - Wikipedia
. … Nws qhov kev nkag mus tsis zoo ntawm cov hlab ntsha hauv lub hlwb ua rau nws muaj txiaj ntsig zoo rau kev sib txawv ntawm qhov nruab nrab thiab qhov nruab nrab ntawm cov agonists ntawm nAChRs.
Puas yog hexamethonium cuam tshuam cov lus teb rau acetylcholine?
Nws tsis muaj qhov cuam tshuamntawm muscarinic acetylcholine receptors (mAChR) nyob rau hauv lub hom phiaj ntawm lub paj hlwb parasympathetic tab sis ua raws li tus antagonist ntawm nicotinic acetylcholine receptors nyob rau hauv sympathetic. thiab parasympathetic ganglia (nAChR).
Hexamethonium yog siv los kho dab tsi?
Hexamethonium yog ib qho ganglionic blocker uas yog siv los kho hypertension (10, 11). Nws tau raug tshaj tawm tias hexamethonium ua rau txo cov ntshav siab ntau dua hauv cov nas angiotensin II-induced hypertensive nas piv nrog cov nas dej ntsev (12).
Dab tsi tshuaj thaiv cov receptors rauacetylcholine yog dab tsi?
Anticholinergics yog cov tshuaj uas thaiv qhov kev ua ntawm acetylcholine. Acetylcholine yog ib qho neurotransmitter, los yog tshuaj xa xov.
Yuav ua li cas thiaj ua tau ganglion blocker?
Ganglion blockers ua los ntawm nyob ntawm qhov chaw receptor ntawm lub post-ganglionic axon kom stabilize daim nyias nyias tawm tsam acetylcholine stimulation. Cov tshuaj no tsis muaj kev cuam tshuam rau pre-ganglionic acetylcholine tso tawm, cholinesterase kev ua, post-ganglionic neuronal catecholamine tso tawm, los yog vascular du nqaij contractility.
