Acetylcholine slows lub plawv dhia los ntawm ua kom lub M2 muscarinic receptor muscarinic receptor Cov tshuaj nrog muscarinic antagonist kev ua tau dav siv hauv tshuaj, hauv kev kho mob plawv tsis tshua muaj, zais zis ntau dhau, teeb meem ua pa xws li mob hawb pob. thiab COPD, thiab cov teeb meem neurological xws li Parkinson's disease thiab Alzheimer's disease. https://en.wikipedia.org › wiki › Muscarinic_antagonist
Muscarinic antagonist - Wikipedia
(M2R) uas, dhau los, qhib lub acetylcholine-activated potassium channel (IK, ACh) txhawm rau txhawm rau txhawm rau tua cov kab mob ntawm cov kab mob sinus ntawm lub sinus node Lub sinoatrial node (tseem hu ua sinuatrial node, SA node los yog sinus node) yog ib pawg ntawm cov hlwb nyob hauv phab ntsa ntawm txoj cai atrium ntawm lub siab. https://en.wikipedia.org › wiki › Sinoatrial_node
Sinoatrial node - Wikipedia
Vim li cas ACh thiaj txo lub plawv dhia?
Kev khi ntawm acetylcholine rau M2 receptors ua haujlwm ua rau lub plawv dhia qeeb kom txog thaum nws mus txog qhov qub sinus atherosclerosis. Qhov no yog ua tiav los ntawm qeeb tus nqi ntawm depolarization, ntxiv rau los ntawm kev txo qis kev tshaj tawm los ntawm lub atrioventricular node.
Acetylcholine txo cov ntshav siab li cas?
Note: tom qab tswj hwm ntawm i.v. bolus, acetylcholine yuav txhawb nqa muscarinic receptors nyob rau ntawm vascular endothelium, ua rau kev tso tawm.ntawmnitric oxide. Nitric oxide yuav so cov leeg nqaij leeg, ua rau poob ntawm cov ntshav siab.
Acetylcholine yuav ua li cas cuam tshuam lub plawv dhia vs norepinephrine?
Norepinephrine, tso tawm los ntawm cov hlab ntsha hauv lub siab, thiab epinephrine, tso tawm los ntawm cov qog adrenal, ua kom lub plawv dhia, hos acetylcholine, tso tawm los ntawm cov hlab ntsha parasympathetic, txo nws.
ACh inhibit cardiac leeg li cas?
Thaum acetylcholine khi rau acetylcholine receptors ntawm cov leeg nqaij pob txha, nws qhib ligand-gated sodium channels hauv cell membrane. … Txawm hais tias acetylcholine induces contraction ntawm skeletal nqaij, nws ua ntawm ntau hom receptor inhibit qhov contraction ntawm cov leeg nqaij fibers.
