Txhua qhov xwm txheej uas tuaj yeem ua rau acidosis, xws li kis kab mob lossis lub cev qhuav dej heev, tuaj yeem ua rau mob. Ntau yam tsis zoo thiab kev hloov ib puag ncig, xws li qaug zog, raug mob khaub thuas, thiab kev ntxhov siab ntawm kev puas siab puas ntsws, tuaj yeem cuam tshuam cov txheej txheem mob.
Dab tsi ua rau mob?
Sickle cell anemia yog tshwm sim los ntawm mutation hauv cov noobuas qhia koj lub cev ua kom cov hlau nplua nuj nyob hauv cov ntshav uas ua rau cov ntshav liab thiab ua rau cov qe ntshav liab nqa oxygen los ntawm Koj lub ntsws thoob plaws hauv koj lub cev (hemoglobin).
Dab tsi ua rau mob ntshav liab?
Nrog oxygen tsawg, qhov txawv txav hemoglobin S gene tuaj yeem ua rau cov protein tsis muaj kuab lom los tsim hauv cov qe ntshav liab. Cov kab nrib pleb no tuaj yeem hloov cov duab ntawm tes, ua rau cov qe ntshav liab muaj mob uas muab tus kab mob nws lub npe.
Dab tsi txhawb RBC mob?
Under deoxygenation, the HbS polymerizes, uas ua rau mob ntawm cov qe ntshav liab (RBCs). Sickled RBCs yog qhov yooj yim heev thiab nruj. Cov yam ntxwv txawv txav no ntawm cov kab mob RBCs ntseeg tau tias yog lub luag haujlwm rau mob ntshav qab zib thiab nquag thiab rov mob vaso-occlusive crises, ntsig txog.
Vim li cas acidosis ua rau mob?
Lub hauv paus ua rau cov kab mob no yog synthesis ntawm ib qho txawv txav Hb (HbS) uas polymerizes nyob rau hauv deoxygenated tej yam kev mob, ua rau mob ntawm tus kab mob.cov qe ntshav liab. Acidosis tau lees paub zoo tias yog tus txhawb nqa ntawm HbS polymerization thiab yog li kev mob ntshav liab.
