Pathogen txuam nrog cov qauv molecular (PAMP) yog molecules nrog kev txuag motifs uas cuam tshuam nrog cov kab mob kab mobuas ua haujlwm li ligands rau tus tswv qauv kev paub txog molecules xws li Kev Hu Xov Tooj Zoo li receptors.
Qhov twg ntawm cov no yog cov piv txwv ntawm cov kab mob cuam tshuam nrog cov qauv molecular?
Piv txwv suav nrog LPS, porins, peptidoglycan, lipoteichoic acids, mannose-nplua nuj glycans, flagellin, kab mob thiab kab mob genomes, mycolic acid, thiab lipoarabinomannan.
PAMPs thiab PRR yog dab tsi?
Abstract. Cov ntsiab lus: Lub cev tiv thaiv kab mob hauv lub cev yog thawj kab ntawm kev tiv thaiv tawm tsam cov kab mob microbial thiab tso siab rau tsev neeg loj ntawmqauv lees paub receptors (PRRs), uas txheeb xyuas qhov sib txawv evolutionarily kev txuag cov qauv ntawm cov kab mob, hu ua Pathogen-associated molecular qauv (PAMPs).
Cov piv txwv ntawm PAMPs yog dab tsi?
Cov piv txwv zoo tshaj plaws ntawm PAMPs suav nrog lipopolysaccharide (LPS) ntawm cov kab mob gram-negative; lipoteichoic acids (LTA) ntawm cov kab mob gram-positive; peptidoglycan; lipoproteins tsim los ntawm palmitylation ntawm N-terminal cysteine ntawm ntau cov kab mob cell phab ntsa proteins; lipoarabinomanan ntawm mycobacteria; ob-stranded RNA…
Dab tsi yog microbe txuam nrog molecular qauv?
Microbe-associated molecular patterns (MAMPs) yog molecular kos npe uas tau txais txiaj ntsig zoo hauv tag nrho cov chav kawm ntawmmicrobes tab sis tsis tuaj ntawm tus tswv tsev, xws li chitin rau fungi thiab flagellin rau cov kab mob (Boller thiab Felix, 2009).
