Definition: Lub hloov pauv ntawm alkyl chloride, alkyl bromide lossis alkyl sulfonate ester rau alkyl iodide los ntawm SN2 hloov pauv. Cov tshuaj tiv thaiv yog nyob ntawm qhov sib npaug raug thawb kom tiav los ntawm nag lossis daus.
Finkelstein cov tshuaj tiv thaiv yog dab tsi muab piv txwv?
Finkelstein cov tshuaj tiv thaiv: Ib qho SN 2 cov tshuaj tiv thaiv uas ib qho halogen atom (cov pab pawg tawm) hloov los ntawm lwm lub halogen atom (lub nucleophile). Hauv qhov piv txwv no ntawm Finkelstein cov tshuaj tiv thaiv,1-chloro-2-phenylethane (ib qho alkyl halide) yog kho nrogsodium iodide (lub nucleophile) los tsim 1-iodo-2-phenylethane.
Finkelstein reagent yog dab tsi?
Abstract. Lub npaj ntawm alkyl iodide los ntawm alkyl bromide los yog chloride nrog poov tshuaj los yog sodium iodide hauv acetone feem ntau hu ua Finkelstein cov tshuaj tiv thaiv. Cov tshuaj tiv thaiv no yog ib qho yooj yim nucleophilic hloov pauv (feem ntau ntawm SN 2) thiab iodide pom tias muaj zog nucleophile dua bromide lossis chloride.
Qhov twg hauv qab no yog Finkelstein kev sib pauv hloov pauv?
Finkelstein cov tshuaj tiv thaiv yog SN2 uas ib qho halogen pauv nrog lwm tus nyob rau hauv lub xub ntiag acetone. Cov halogens no suav nrog chloride thiab bromide reacting nrog lwm cov alkyl halide zoo li sodium iodide. Ua kom tiav cov lus teb: Cov ntsiab lus tsis yog xim hlau ntawm pawg 17 ntawm lub sijhawm lub sijhawm hu ua halogens.
Qhov twg Finkelstein cov tshuaj tiv thaiv feem ntau tshwm sim?
Tertiaryamines nrog sib txawv R pawg cleave kom cov reactive tshaj plaws alkyl bromideyog tsim. Benzyl thiab allyl cleave zoo dua alkyl, qis alkyl cleaves zoo dua alkyl siab dua thiab aryl tsis cleaved kiag li.
