Kev tshawb pom ntawm cov paj hlwb loj hlob (NGF) los ntawm Rita Levi-Montalcini hauv xyoo 1950 yog qhov tseem ceeb hauv cov txheej txheem uas coj mus rau niaj hnub cell biology.
Rita Levi-Montalcini nrhiav tau paj hlwb loj hlob li cas?
Xyoo 1948 nws tau tshawb pom hauv Hamburger lub chaw kuaj mob ntau tus nas qog ua rau lub paj hlwb loj hlob thaum cog rau hauv qaib embryo. Levi-Montalcini thiab Hamburger taug qab cov nyhuv rau cov khoom hauv cov qog uas lawv hu ua paj hlwb loj hlob (NGF).
EGF nrhiav tau li cas?
Lawv tau ua haujlwm ua ke hauv Viktor Hamburger lub chaw kuaj mob ntawm Washington University hauv St. Louis. Thawj qhov qhia txog kev loj hlob ntawm tus kab mob epidermal tau pom nyob rau hauv cov nas me nyuam yug los txhaj nrog cov kua qaub los ntawm cov qog qaub ncaug nas. … Cohen tau luam tawm thawj qhov kev tshawb pom ntawm EGF xyoo 1960.
NGF txheeb tau li cas?
NGF tau tshawb pom dhau ntawm cov kev sim hauv xyoo 1950 ntawm kev txhim kho ntawm cov nqaij qaib paj hlwb. Txij li thaum nws tshawb pom, NGF tau pom los ua ntau yam ntaub so ntswg thoob plaws hauv kev loj hlob thiab kev laus. … Nws pom tau tias cov qog nqaij hlav muaj peev xwm ua rau cov hlab ntsha loj hlob tuaj.
NGF nyob qhov twg?
NGF yog tsim los ntawm txhua lub peripheral cov ntaub so ntswg / khoom nruab nrog uas yog innervated los ntawm kev hnov lus afferents thiab / los yog sympathetic efferents, nrog rau hauv nruab nrab thiab peripheral paj hlwb thiabimmune cells.
