Chromosomal deletions tshwm sim nyob rau hauv ib tug tsawg zaus, los yog induced los ntawm kho cov kab mob hlwb (zoo tshaj, laus los yog maturing oocytes nyob rau hauv cov poj niam, thiab postmeiotic spermatogenic hlwb nyob rau hauv lub txiv neej) nrog chromosome-breaking agents, xws li mob hluav taws xob los yog tej yam tshuaj.
Ntau npaum li cas chromosomal deletions?
22q11 deletion syndrome yog qhov tshwm sim ntau tshaj plaws ntawm tib neeg chromosomal deletion syndrome tshwm sim hauv kwv yees li 1 ntawm 4000-6000 tus menyuam yug nyob[32].
Dab tsi ua rau kev hloov pauv hloov?
Ib deletion mutation tshwm sim thaum ib daim ntawv wrinkle ntawm DNA template strand thiab tom qab ntawd ua rau ib tug nucleotide raug tshem tawm ntawm replicated strand(Daim duab 3). Daim duab 3: Hauv kev hloov pauv hloov pauv, cov ntaub ntawv wrinkle ntawm DNA qauv strand, uas ua rau cov nucleotide raug tshem tawm los ntawm cov kab rov ua dua.
Dab tsi ua rau chromosome poob?
Chromosome abnormalities feem ntau tshwm sim los ntawm ib los yog ntau tshaj ntawm cov no: Yam yuam kev thaum faib cov hlwb sib deev (meiosis) yuam kev thaum faib lwm lub hlwb (mitosis) raug rau cov tshuaj uas ua rau yug tsis xws luag (teratogens)
Puas yog chromosomal deletions tau txais txiaj ntsig?
Txawm hais tias nws muaj peev xwm ua tau los ntawm qee hom chromosomal abnormalities, feem ntau cov kab mob chromosomal (xws li Down syndrome thiab Turner syndrome) yog tsis dhau los ntawm ib tiam mus rau lwm tiam.
