2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Tsis muaj kev cai tshwj xeeb txwv tsis pub siv cov noob rau cov hom phiaj kho kom zoo nkauj, thiab txog thaum nyuam qhuav tsis zoo li tsim nyog. Tab sis nyob rau lub Peb Hlis, tom qab lub hlis ntawm kev sib cav sab hauv, NIH cov neeg ua haujlwm tau hloov qhov sib npaug los ntawm kev pom zoo thawj zaug kev sim tshuaj gene rau cov neeg uas tsis muaj mob.
Kev siv noob caj noob ces siv tau li cas?
Kev kho noob hloov pauv cov noob tsis raug lossis ntxiv cov noob tshiab hauv sim kho tus kab moblossis txhim kho koj lub cev muaj peev xwm tiv thaiv kab mob. Gene therapy tuav cov lus cog tseg rau kev kho ntau yam kab mob, xws li mob qog noj ntshav, cystic fibrosis, kab mob plawv, ntshav qab zib, hemophilia thiab AIDS.
Puas siv tshuaj kho noob tsuas yog siv rau kev kho mob?
Gene therapy yog tam sim no kuaj tsuas yog rau cov kab mob uas tsis muaj lwm yam kev kho.
Thaum twg tau siv tshuaj kho noob?
Tom qab 18 xyoo ntawm kev tshawb fawb ntxiv, thawj qhov kev sim tshuaj noob tau pib hauv 1990. Ib tug ntxhais plaub xyoos hu ua Ashanthi DeSilva tau txais kev kho mob 12-hnub rau cov kab mob tsis tshua muaj caj ces hu ua kev tiv thaiv kab mob hnyav.
Puas tau tuag los ntawm kev kho noob?
Peb tus menyuam uas muaj kab mob tsis tshua muaj kab mob neuromuscular tau tuag tom qab tau txais koob tshuaj ntau ntawm kev kho noob hauv kev sim tshuaj los ntawm Audentes Therapeutics.
Pom zoo:
Pob noob noob noob noob nom noob tswv los?
Cov noob noob hnav tuaj yeem tshwm sim hauv Asia lossis East Africa, thiab cov neeg Iyiv thaum ub tau paub tias tau siv cov noob hauv av ua hmoov nplej. Cov noob tau siv los ntawm Suav tsawg kawg yog 5,000 xyoo dhau los, thiab ntau pua xyoo lawv tau hlawv cov roj los ua cov tshuaj tsw qab rau cov ntawv suav zoo tshaj plaws.
Yuav ua li cas txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau pom kev pom?
Txawm li cas los xij, corneal collagen cross-linking - cov txheej txheem qib siab tau pom zoo los ntawm US Food and Drug Administration (FDA) hauv xyoo 2016 - tuaj yeem txhim kho qhov pom kev hauv cov neeg mob txhua hnub nyoog. Corneal collagen cross-linking (CXL) tsis yog kho rau keratoconus, tab sis nws tuaj yeem pab tiv thaiv tus mob kom tsis txhob mob hnyav.
Qhov twg yog kev zoo nkauj lossis kev zoo nkauj?
Feem ntau, feem ntau siv, cov ntsiab lus, ntau daim ntawv yuav zoo nkauj. Txawm li cas los xij, hauv ntau cov ntsiab lus tshwj xeeb, ntau daim ntawv tuaj yeem ua tau zoo nkauj xws li. nyob rau hauv kev siv rau ntau hom kev zoo nkauj los yog sau ntawm beauties.
Puas muaj cov dej tsis huv rau kev txhaj tshuaj rau kev siv tshuaj?
dej tsis huv rau nqus tau. Cov dej no feem ntau yog npaj rau siv nrog inhalators thiab npaj cov tshuaj inhalation. Nws nqa cov ntsiab lus nruj me ntsis rau cov kab mob endotoxins ntau dua li tsis muaj WFI thiab, yog li ntawd, tsis haum rau kev siv parenteral.
Dab tsi yog qhov kev txhim kho tsis ntev los no hauv kev kho noob?
Cov txiaj ntsig: Ntau hom tshuaj kho ntau yam tau raug tshawb xyuas, xws li qog nqaij hlav, tua tus kheej, antiangiogenesis, inflammatory cytokine thiab micro-RNA noob. Kev nce qib tsis ntev los no txhawj xeeb cov kab mob tshiab, xws li cov kab mob oncolytic, thiab kev sib koom ua ke ntawm kev kho cov noob kab mob, kws khomob thiab kev kho hluav taws xob.
