2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Glycosylation yog qhov tseem ceeb ntawm txoj hauv kev biosynthetic-secretory hauv endoplasmic reticulum (ER) thiab Golgi apparatus. Kwv yees li ib nrab ntawm tag nrho cov proteins feem ntau qhia hauv lub xovtooj ntawm qhov kev hloov pauv no, uas suav nrog covalent ntxiv ntawm cov piam thaj moieties rau cov amino acids tshwj xeeb.
protein glycosylation tshwm sim nyob qhov twg?
Glycosylation yog qhov txuas ntawm cov piam thaj molecules rau cov proteins los ntawm kev sib txuas glycosidic. Nws tshwm sim nyob rau hauv ER (Endoplasmic Reticulum) thiab Golgi complex lub cev ntawm tes. Yog li glycosylation ntawm supermolecules tshwm sim hauv Endoplasmic reticulum.
Dab tsi ua rau glycosylation ntawm cov proteins?
Protein glycosylation yog hom kev hloov pauv hloov pauv ntau tshaj plaws (PTM) ntawm cov khoom tawm thiab cov cellular membrane-associated proteins (Spiro, 2002). Nws suav nrog qhov kev sib txuas ntawm ntau hom glycans(tseem hu ua carbohydrates, saccharides, lossis qab zib) rau cov protein.
Puas glycosylation tshwm sim ua ntej lossis tom qab cov protein tau muab tais?
Technically, N-glycosylation pib ua ntej cov protein txawm yog txhais, raws li dolicol pyrophosphate oligosaccharide (piv txwv li qab zib "ntoo" - tsis yog lub ntsiab lus, los ntawm txoj kev.) yog synthesized hauv ER (Daim duab 11.4.
Glycosylation tshwm sim li cas?
Glycosylation yog txheej txheem uas yog carbohydratecovalently txuas mus rau lub hom phiaj macromolecule, feem ntau cov proteins thiab lipids. Qhov kev hloov kho no ua haujlwm rau ntau yam haujlwm. … Hauv lwm qhov xwm txheej, cov proteins tsis ruaj khov tshwj tsis yog lawv muaj oligosaccharides txuas ntawm amide nitrogen ntawm qee yam asparagine residues.
Pom zoo:
Thaum twg pfizer tshwm sim tshwm sim?
Qee yam tshwm sim tshwm sim txoj cai tom qab koj txhaj tshuaj, zoo li mob me me hauv koj txhais caj npab. Lwm tus yuav siv sij hawm ntau teev los txhim kho. Nco ntsoov tias nrog ob koob tshuaj tiv thaiv zoo li Pfizer-BioNTech thiab Moderna, koj tuaj yeem pom muaj kev phiv ntau dua tom qab txhaj tshuaj thib ob.
Dab tsi ntawm cov hauv qab no yog qhov tshwm sim ntawm kev sib ntaus sib tua ntawm lub pas dej brandywine?
Cov txiaj ntsig ntawm Kev Sib Tw ntawm Brandywine Creek yog dab tsi? Washington tsuas yog sim ncua kev ntes Philadelphia kom nws ua tiav li no. Cov tub rog Asmeskas tsis tau poob siab ntau thiab lawv tau khiav tawm ntawm British. Washington tseem tuaj yeem kawm los ntawm nws qhov yuam kev ntawm kev tso nws txoj cai sab xis qhib.
Thaum twg qhov kev rov tshwm sim tshwm sim?
Thaum Replevin tuaj yeem thov Li no, qhov no yog qhov xwm txheej tshwm sim ntau tshaj plaws uas yuav tshwm sim thaum tus neeg siv khoom tsis raug them nyiaj qiv tsheb. Kev ua txhaum cai ntawm kev thaj yeeb nyab xeeb yog me ntsis luv luv. Nws tsis suav nrog kev txeeb tsheb yam tsis tau ceeb toom lossis kub xov tooj kom tsav tsheb mus.
Puas khaws cov ntaub ntawv hais txog qhov twg thaum twg thiab dab tsi ntawm lub neej tshwm sim?
Kev tuav ntaub ntawv hais txog qhov twg, thaum twg, thiab dab tsi ntawm lub neej tshwm sim - uas yog, tib neeg nco ntsoov lub neej ntu. … Cov txheej txheem los ntawm kev ntsib yav dhau los nrog ib puag ncig cuam tshuam rau txoj hauv kev uas tib neeg nkag mus, ua kev xav txog, thiab khaws cov ntaub ntawv.
Thaum qhov no yog qhov tshwm sim uas tshwm sim?
Lub hauv paus ntsiab lus ntawm kev mob Nrog qhov tshwm sim (uppada) ntawm qhov no, qhov tshwm sim. Thaum tsis muaj qhov no, qhov ntawd tsis tuaj. Nrog lub cessation (nirodha) ntawm no, uas ceases. - Samyutta Nikaya 12.61. Thaum qhov no yog qhov tshwm sim uas tshwm sim qhov tshwm sim uas tshwm sim thaum qhov no tsis yog qhov tsis yog qhov kev txiav txim siab tsis piav qhia?
