Vim li cas thiaj muab leucovorin nrog pyrimethamine?

Cov txheej txheem:

Vim li cas thiaj muab leucovorin nrog pyrimethamine?
Vim li cas thiaj muab leucovorin nrog pyrimethamine?
Anonim

Leucovorin tiv thaiv cov pob txha pob txha los ntawm cov tshuaj lom ntawm pyrimethamine. Ib qho tshuaj thib ob, xws li sulfadiazine lossis clindamycin (yog tias tus neeg mob muaj qhov tsis txaus siab rau cov tshuaj sulfa), yuav tsum tau suav nrog.

YPuas yog pyrimethamine ib qho kua qaub lossis lub hauv paus?

Ib tshuaj tiv thaiv kab mob. Pyrimethamine yog ib qho aminopyrimidineuas yog pyrimidine-2, 4-diamine uas tau hloov ntawm txoj hauj lwm 5 los ntawm pawg p-chlorophenyl thiab ntawm txoj hauj lwm 6 los ntawm pawg ethyl. Nws yog cov tshuaj folic acid antagonist siv los ua tshuaj tiv thaiv kab mob los yog nrog sulfonamide los kho toxoplasmosis.

Yuav ua li cas yog qhov kev txiav txim ntawm pyrimethamine?

Mechanism of action and resistance

Pyrimethamine xaiv inhibits plasmodial daim ntawv ntawm dihydrofolate reductase, txo cov tshuaj folic acid xav tau rau nucleic acid synthesis hauv malarial parasite. (saib daim duab 51.4).

Kev kho mob toxoplasmosis zoo tshaj yog dab tsi?

Cov neeg noj qab haus huv feem ntau rov qab los ntawm toxoplasmosis yam tsis tau kho. Cov neeg mob tuaj yeem kho nrog kev sib xyaw ua ke ntawm cov tshuaj xws li pyrimethamine thiab sulfadiazine, ntxiv rau flinic acid.

Yuav siv tshuaj tua kab mob dab tsi los kho toxoplasmosis?

Tshuaj Tiv Thaiv Kab Mob

Pyrimethamine, clindamycin, thiab folinic acid . Atovaquone (ib qho tshuaj tua kab mob muaj zog) siv nrog pyrimethamine thiab folinic acid. Azithromycin (lwm yamtshuaj tua kab mob), pyrimethamine, thiab folinic acid. Atovaquone thiab sulfadiazine.

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