Txawm hais tias qhov chaw kho mob tseem ceeb cuam tshuam ntawm PPIs tuaj yeem tshwm sim, ib yam li lwm yam tshuaj, cov tshuaj no tsis nquag pom thaum lub sijhawm lossis tom qab tswj hwm. Yog li, PPIs raug suav tias muaj kev nyab xeeb thiab suav tias yog qhov txiaj ntsig zoo.
Cov kev mob tshwm sim ntev npaum li cas ntawm proton twj tso kua mis inhibitors?
Txawm hais tias PPIs tau muaj kev txhawb nqa kev nyab xeeb, kev tshawb fawb tsis ntev los no hais txog kev siv cov tshuaj PPI mus sij hawm ntev tau sau tseg tias muaj kev phom sij, suav nrog kev pheej hmoo ntawm pob txha, mob ntsws, Clostridium difficile diarrhea, hypomagnesemia, vitamin B12 deficiency, mob raum mob, thiab dementia.
Vim li cas proton twj tso kua mis inhibitors tsis zoo rau koj?
PPI kev siv tau cuam tshuam nrog muaj kev pheej hmoo ntau ntxiv ntawm kev tsim kab mob ntsws hauv zej zog (CAP). Kev tshem tawm cov kua qaub ua rau muaj kev nce hauv plab pH, tso cai rau kev loj hlob ntawm cov kab mob uas tsis yog Helicobacter pylori hauv cov kua txiv hmab txiv ntoo, plab hnyuv, thiab duodenum.
Dab tsi yog qhov zoo tshaj plaws proton twj tso kua mis inhibitor?
Cov kws sau ntawv tau tshuaj xyuas 41 cov kev tshawb fawb txog kev ua tau zoo ntawm PPIs. Lawv xaus lus tias muaj qhov sib txawv me ntsis ntawm qhov ua tau zoo ntawm PPIs. Yog li, thaum muaj qee cov ntaub ntawv los qhia tias esomeprazoleua tau zoo dua ntawm kev txo cov tsos mob, feem ntau cov kws tshaj lij pom zoo tias PPIs muaj cov txiaj ntsig zoo sib xws.
PPI qis tshaj yog dab tsi?
Rabeprazole thiabpantoprazole (IC₅₀=≥ 25 μM) yog qhov tsis muaj zog tshaj plaws.