Deamidation yog hais txog the hydrolysis ntawm amide sab saw ntawm Asn thiab Gln residues los tsim lawv cov carboxylic acid derivatives (Aswad, Paranandi, & Schurter, 2000; Los ntawm: Advances hauv Protein Chemistry thiab Structural Biology, 2018.
Dab tsi yog qhov tshuaj tiv thaiv deamidation?
Deamidation yog tshuaj tiv thaiv uas ib pawg amide ua haujlwm nyob rau hauv cov saw ntawm cov amino acids asparagine lossis glutamine raug tshem tawm lossis hloov mus rau lwm pab pawg ua haujlwm. Feem ntau, asparagine hloov mus rau aspartic acid lossis isoaspartic acid.
Lub hom phiaj ntawm kev deamimidation yog dab tsi?
Deamidation feem ntau cuam tshuam rau asparagine (Asn lossis N) cov khoom seem ntawm cov protein, tab sis tuaj yeem cuam tshuam rau glutamine (Gln lossis Q) cov seem. 5 Deamidation hauv vivo tau xav tias ua lub luag haujlwm tseem ceeb hauv kev laus, ua raws li lub sijhawm molecular rau qee cov txheej txheem lom neeg.
deamination txhais li cas?
Deamination yog kev tshem tawm ntawm pawg amino los ntawm cov molecule. Enzymes uas catalyze cov tshuaj tiv thaiv no hu ua deaminases. … Nyob rau hauv cov xwm txheej ntawm kev noj cov protein ntau, deamination yog siv los rhuav tshem cov amino acids rau lub zog. Cov amino pawg raug tshem tawm ntawm cov amino acid thiab hloov mus rau ammonia.
Dab tsi yog qhov txawv ntawm deamidation thiab deamination?
Raws li nouns qhov txawv ntawm deamidation thiab deamination
yog tias deamidation yog (biochemistry) hloov dua siab tshiab ntawmglutamine, asparagine, glutamine residues nyob rau hauv ib tug polypeptide rau glutamic acid los yog aspartic acid los ntawm kev kho mob nrog muaj zog acid, transamidase los yog deamidase thaum deamination yog deamination.
