Basophils tsiv mus rau qhov chaw raug mob thiab hla lub capillary endothelium txhawm rau txhawm rau hauv cov ntaub so ntswg puas, qhov uas lawv tso cov granules uas muaj histamine (ua kom cov hlab ntsha) thiab heparin (tiv thaiv cov hlab ntsha).
Pob basophils tso histamine?
Mast cells thiab basophils sawv cev qhov tseem ceeb tshaj plaws ntawm histamine hauv lub cev tiv thaiv kab mob. Histamine khaws cia hauv cytoplasmic granules nrog rau lwm cov amines (piv txwv li, serotonin), proteases, proteoglycans, cytokines / chemokines, thiab angiogenic yam thiab sai sai tso tawm thaum ua rau muaj ntau yam stimuli.
Vim li cas basophils zais histamine?
Basophils muaj cov tshuaj tiv thaiv coagulant heparin, uas tiv thaiv cov ntshav los ntawm kev txhaws sai heev. Lawv kuj muaj cov vasodilator histamine, uas txhawb cov ntshav ntws mus rau cov ntaub so ntswg. Lawv tuaj yeem pom muaj ntau qhov txawv txav ntawm qhov chaw ntawm tus kab mob exoparasite, piv txwv li, zuam.
Dab tsi ua rau basophils tso tawm histamine?
Interleukin-5
Basophils tsim cov tshuaj histamine thiab leukotriene, uas tso tawm ntawm qhov chaw mob. Complement C5a los ntawm nws tus kheej ua rau cov tshuaj histamine tso tawm, txawm hais tias basophils primed nrog IL-5 qhia txog kev tso tawm histamine thiab tseem tsim cov leukotriene C4 ntau hauv cov lus teb rau C5a.
Vim li cas basophils txhawb kev mob?
Basophils qhib los ntawm IgE paub tso tawm histamine thiab LTC4 los txhawbmob18.
