Diazotized sulfanilic acid li ib qho tshiab reagent rau kev tshawb pom ntawm phenothiazine phenothiazine Phenothiazine yog ib chav kawm ntawm thawj tiam heterocyclic anti-psychotic tshuaj, uas tso tawm cov kev ua ub no ntawm dopamine receptors thiab Tsis ntev los no tau pom tias muaj peev xwm tiv thaiv neoplastic. https://www.ncbi.nlm.nih.gov › books › NBK556113
Phenothiazine - StatPearls - NCBI Bookshelf
, cov tshuaj zoo li phenothiazine thiab lawv cov khoom decomposition hauv tshuaj. Pharmazie.
sulfanilic acid siv rau dab tsi?
Lawv yog cov derivatives ntawm sulfanilic acid (p-aminobenzenesulfonic acid), thiab lawv yog siv rau prophylactic thiab kho cov kab mob tshwm sim los ntawm gram-positive thiab gram-negative kab mobthiab qee cov protozoa (ua rau cov kab mob malaria, toxoplasmosis, thiab lwm yam).
Yuav ua li cas yog diazotized sulfanilic acid siv?
Van den Bergh tshuaj tiv thaiv uas yog siv los ntsuas qib bilirubin, ob peb bilirubin nrog diazotized sulfanilic acid. Cov tshuaj tiv thaiv no ua rau azo pigments, lossis azobilirubin. Lub xub ntiag ntawm azobilirubin yog qhov zoo tshaj plaws qhia los ntawm qhov tshwm sim ntawm cov xim liab-liab.
Lub hauv paus ntsiab lus ntawm bilirubin thiab sulfanilic acid cov tshuaj tiv thaiv yog dab tsi?
Bilirubin reacts nrog diazotized sulfanilic acid los tsim cov azo dye uas yog xim liab hauv nruab nrab thiab xiav hauv cov tshuaj alkaline. Thaum cov dej-soluble bilirubinglucuronides reacts "ncaj qha", cov dawb "indirect" bilirubin reacts tsuas yog nyob rau hauv lub xub ntiag ntawm ib tug accelerator.
Diazo method yog dab tsi?
The DxC800 siv lub sijhawm kawg ntawm Diazo txoj kev (Jendrassik-Grof) ntsuas qhov concentration ntawm tag nrho bilirubin hauv cov ntshav los yog ntshav. Nyob rau hauv cov tshuaj tiv thaiv, bilirubin reacts nrog diazo reagent nyob rau hauv lub xub ntiag ntawm caffeine, benzoate, thiab acetate ua accelerators rau tsim azobilirubin.
